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CYP2C76 deficiency is embryonic lethal in cynomolgus macaques: The potential role of CYP2C76 in early embryogenesis.
Koyama, Shuzo; Fukuda, Koji; Watanabe, Sho; Matsushita, Akinori; Tsuchiya, Hideaki; Fujinami, Nahoko; Kohara, Sakae; Murayama, Norie; Nagano, Masashi; Yamazaki, Hiroshi; Fukuzaki, Koichiro; Uno, Yasuhiro; Hosoi, Yoshihiko.
Affiliation
  • Koyama S; Drug Safety Research Center (DSR), Shin Nippon Biomedical Laboratories (SNBL), Ltd., Kagoshima, Japan; SNBL USA, Ltd., Everett, WA, USA.
  • Fukuda K; Drug Safety Research Center (DSR), Shin Nippon Biomedical Laboratories (SNBL), Ltd., Kagoshima, Japan; SNBL USA, Ltd., Everett, WA, USA.
  • Watanabe S; Drug Safety Research Center (DSR), Shin Nippon Biomedical Laboratories (SNBL), Ltd., Kagoshima, Japan; SNBL USA, Ltd., Everett, WA, USA.
  • Matsushita A; Drug Safety Research Center (DSR), Shin Nippon Biomedical Laboratories (SNBL), Ltd., Kagoshima, Japan; Pharmacokinetics and Bioanalysis Center (PBC), Shin Nippon Biomedical Laboratories (SNBL), Ltd., Kainan, Japan.
  • Tsuchiya H; Research Center for Animal Life Science, Shiga University of Medical Science, Otsu, Japan.
  • Fujinami N; Graduate School of Biology-Oriented Science and Technology, Kinki University, Kinokawa, Japan.
  • Kohara S; Pharmacokinetics and Bioanalysis Center (PBC), Shin Nippon Biomedical Laboratories (SNBL), Ltd., Kainan, Japan.
  • Murayama N; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Japan.
  • Nagano M; Laboratory of Theriogenology, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
  • Yamazaki H; Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Japan.
  • Fukuzaki K; Drug Safety Research Center (DSR), Shin Nippon Biomedical Laboratories (SNBL), Ltd., Kagoshima, Japan; SNBL USA, Ltd., Everett, WA, USA.
  • Uno Y; Pharmacokinetics and Bioanalysis Center (PBC), Shin Nippon Biomedical Laboratories (SNBL), Ltd., Kainan, Japan. Electronic address: uno-yasuhiro@snbl.co.jp.
  • Hosoi Y; Graduate School of Biology-Oriented Science and Technology, Kinki University, Kinokawa, Japan. Electronic address: Hosoi@waka.kindai.ac.jp.
Drug Metab Pharmacokinet ; 32(1): 112-115, 2017 Feb.
Article in En | MEDLINE | ID: mdl-28153493
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 Enzyme System / Embryonic Development / Embryo Loss / Macaca fascicularis Limits: Animals Language: En Journal: Drug Metab Pharmacokinet Journal subject: FARMACOLOGIA / METABOLISMO Year: 2017 Document type: Article Affiliation country: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 Enzyme System / Embryonic Development / Embryo Loss / Macaca fascicularis Limits: Animals Language: En Journal: Drug Metab Pharmacokinet Journal subject: FARMACOLOGIA / METABOLISMO Year: 2017 Document type: Article Affiliation country: Estados Unidos