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Expanded safety analysis of pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, in patients with acute myeloid leukemia and myelodysplastic syndromes.
Swords, R T; Watts, J; Erba, H P; Altman, J K; Maris, M; Anwer, F; Hua, Z; Stein, H; Faessel, H; Sedarati, F; Dezube, B J; Giles, F J; Medeiros, B C; DeAngelo, D J.
Affiliation
  • Swords RT; Leukemia Program, Sylvester Comprehensive Cancer Center, Miami, FL, USA.
  • Watts J; Leukemia Program, Sylvester Comprehensive Cancer Center, Miami, FL, USA.
  • Erba HP; Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI, USA.
  • Altman JK; Northwestern Medicine Developmental Therapeutics Institute, Northwestern University, Chicago, IL, USA.
  • Maris M; Colorado Blood Cancer Institute, Denver, CO, USA.
  • Anwer F; University of Arizona Cancer Center, Tucson, AZ, USA.
  • Hua Z; T Takeda Pharmaceuticals International Co., Cambridge, MA, USA.
  • Stein H; T Takeda Pharmaceuticals International Co., Cambridge, MA, USA.
  • Faessel H; T Takeda Pharmaceuticals International Co., Cambridge, MA, USA.
  • Sedarati F; T Takeda Pharmaceuticals International Co., Cambridge, MA, USA.
  • Dezube BJ; T Takeda Pharmaceuticals International Co., Cambridge, MA, USA.
  • Giles FJ; Northwestern Medicine Developmental Therapeutics Institute, Northwestern University, Chicago, IL, USA.
  • Medeiros BC; Division of Hematology, Stanford University School of Medicine, Stanford, CA, USA.
  • DeAngelo DJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Blood Cancer J ; 7(2): e520, 2017 02 03.
Article in En | MEDLINE | ID: mdl-28157218
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Myelodysplastic Syndromes / Leukemia, Myeloid, Acute / Cyclopentanes / Enzyme Inhibitors Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Blood Cancer J Year: 2017 Document type: Article Affiliation country: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Myelodysplastic Syndromes / Leukemia, Myeloid, Acute / Cyclopentanes / Enzyme Inhibitors Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Blood Cancer J Year: 2017 Document type: Article Affiliation country: Estados Unidos