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Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline.
John, Catherine; Soler Artigas, María; Hui, Jennie; Nielsen, Sune Fallgaard; Rafaels, Nicholas; Paré, Peter D; Hansel, Nadia N; Shrine, Nick; Kilty, Iain; Malarstig, Anders; Jelinsky, Scott A; Vedel-Krogh, Signe; Barnes, Kathleen; Hall, Ian P; Beilby, John; Musk, Arthur W; Nordestgaard, Børge G; James, Alan; Wain, Louise V; Tobin, Martin D.
Affiliation
  • John C; Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Leicester, UK.
  • Soler Artigas M; Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Leicester, UK.
  • Hui J; School of Pathology and Laboratory Medicine, The University of Western Australia, Australia.
  • Nielsen SF; PathWest, Department of Health, Government of Western Australia, Perth, WA, Australia.
  • Rafaels N; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Western Australia, Australia.
  • Paré PD; School of Population Health, The University of Western Australia, Australia.
  • Hansel NN; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark.
  • Shrine N; Center for Personalized Medicine and Biomedical Informatics, School of Medicine, University of Colorado, Anschutz Medical Campus.
  • Kilty I; University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada.
  • Malarstig A; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
  • Jelinsky SA; Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Leicester, UK.
  • Vedel-Krogh S; Pfizer Worldwide Research and Development, Cambridge, Massachusetts, USA.
  • Barnes K; Pfizer Worldwide Research and Development, Stockholm, Sweden.
  • Hall IP; Pfizer Worldwide Research and Development, Cambridge, Massachusetts, USA.
  • Beilby J; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark.
  • Musk AW; Center for Personalized Medicine and Biomedical Informatics, School of Medicine, University of Colorado, Anschutz Medical Campus.
  • Nordestgaard BG; Division of Respiratory Medicine, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
  • James A; School of Pathology and Laboratory Medicine, The University of Western Australia, Australia.
  • Wain LV; PathWest, Department of Health, Government of Western Australia, Perth, WA, Australia.
  • Tobin MD; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Western Australia, Australia.
Thorax ; 72(5): 400-408, 2017 05.
Article in En | MEDLINE | ID: mdl-28174340
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiration / Genetic Variation / Pulmonary Disease, Chronic Obstructive Type of study: Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Oceania Language: En Journal: Thorax Year: 2017 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiration / Genetic Variation / Pulmonary Disease, Chronic Obstructive Type of study: Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Country/Region as subject: Oceania Language: En Journal: Thorax Year: 2017 Document type: Article Affiliation country: Reino Unido Country of publication: Reino Unido