Regulation of PI3K signaling in T-cell acute lymphoblastic leukemia: a novel PTEN/Ikaros/miR-26b mechanism reveals a critical targetable role for PIK3CD.

Yuan, T; Yang, Y; Chen, J; Li, W; Li, W; Zhang, Q; Mi, Y; Goswami, R S; You, J Q; Lin, D; Qian, M D; Calin, S; Liang, Y; Miranda, R N; Calin, G A; Zhou, X; Ma, L; Zweidler-McKay, P A; Liu, B; Weng, A P; Medeiros, L J; Zhang, Y; You, M J

Yuan, T; Yang, Y; Chen, J; Li, W; Li, W; Zhang, Q; Mi, Y; Goswami, R S; You, J Q; Lin, D; Qian, M D; Calin, S; Liang, Y; Miranda, R N; Calin, G A; Zhou, X; Ma, L; Zweidler-McKay, P A; Liu, B; Weng, A P; Medeiros, L J; Zhang, Y; You, M J.

Affiliation

Yuan T; Department of Hematopathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Yang Y; Department of Hematology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.
Chen J; Department of Hematopathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Li W; Department of Hematopathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Li W; Shaoxing University Medical School, Shaoxing City, Zhejiang Province, China.
Zhang Q; Department of Hematopathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Mi Y; Department of Laboratory Medicine, Harbin Medical University Tumor Hospital, Heilongjiang Province, Harbin, China.
Goswami RS; Department of Hematopathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
You JQ; Department of Leukemia, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Lin D; Department of Leukemia, Institute of Hematology and Blood Disease Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Qian MD; Department of Hematopathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Calin S; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Liang Y; Department of Molecular and Cellular Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Miranda RN; Department of Hematopathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Calin GA; Department of Immunology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Zhou X; Department of Experimental Therapeutics and Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ma L; Department of Hematopathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Zweidler-McKay PA; Department of Hematopathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Liu B; Shaoxing University Medical School, Shaoxing City, Zhejiang Province, China.
Weng AP; Department of Hematopathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Medeiros LJ; Department of Experimental Therapeutics and Center for RNA Interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Zhang Y; Department of Pathology, Shanghai Cancer Center, Fudan University, Shanghai, China.
You MJ; Department of Experimental Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Leukemia ; 31(11): 2355-2364, 2017 11.

Article in En | MEDLINE | ID: mdl-28280276

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / MicroRNAs / PTEN Phosphohydrolase / Ikaros Transcription Factor / Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Class I Phosphatidylinositol 3-Kinases Type of study: Prognostic_studies Limits: Adolescent / Adult / Aged / Animals / Humans / Middle aged Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Estados Unidos

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