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Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia.
Mohr, Sebastian; Doebele, Carmen; Comoglio, Federico; Berg, Tobias; Beck, Julia; Bohnenberger, Hanibal; Alexe, Gabriela; Corso, Jasmin; Ströbel, Philipp; Wachter, Astrid; Beissbarth, Tim; Schnütgen, Frank; Cremer, Anjali; Haetscher, Nadine; Göllner, Stefanie; Rouhi, Arefeh; Palmqvist, Lars; Rieger, Michael A; Schroeder, Timm; Bönig, Halvard; Müller-Tidow, Carsten; Kuchenbauer, Florian; Schütz, Ekkehard; Green, Anthony R; Urlaub, Henning; Stegmaier, Kimberly; Humphries, R Keith; Serve, Hubert; Oellerich, Thomas.
Affiliation
  • Mohr S; Department of Medicine II, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Doebele C; Department of Medicine II, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Comoglio F; Department of Haematology, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK; Cambridge Institute for Medical Research, Wellcome Trust/MRC Stem Cell Institute, Cambridge CB2 0XY, UK.
  • Berg T; Department of Medicine II, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany; German Cancer Research Center and German Cancer Consortium, 69120 Heidelberg, Germany.
  • Beck J; Chronix Biomedical, Goetheallee 8, 37073 Göttingen, Germany.
  • Bohnenberger H; Institute of Pathology, University Medical Center Göttingen, Robert-Koch-Straße 40, 37073 Göttingen, Germany.
  • Alexe G; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA 02115, USA; Broad Institute, Cambridge, MA 02142, USA.
  • Corso J; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.
  • Ströbel P; Institute of Pathology, University Medical Center Göttingen, Robert-Koch-Straße 40, 37073 Göttingen, Germany.
  • Wachter A; Institute of Medical Statistics, University Medical Center Göttingen, Humboldtallee 32, 37073 Göttingen, Germany.
  • Beissbarth T; Institute of Medical Statistics, University Medical Center Göttingen, Humboldtallee 32, 37073 Göttingen, Germany.
  • Schnütgen F; Department of Medicine II, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Cremer A; Department of Medicine II, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Haetscher N; Department of Medicine II, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
  • Göllner S; Department of Hematology and Oncology, University of Halle, Ernst-Grube-Street 40, 06120 Halle, Germany.
  • Rouhi A; Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
  • Palmqvist L; Department of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Su sahlgrenska, 41345 Gothenburg, Sweden.
  • Rieger MA; Department of Medicine II, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany; German Cancer Research Center and German Cancer Consortium, 69120 Heidelberg, Germany.
  • Schroeder T; Department of Biosystems Science and Engineering, Eidgenössische Technische Hochschule (ETH) Zurich, 4058 Basel, Switzerland.
  • Bönig H; Institute for Transfusion Medicine and Immunohematology, Goethe University, Sandhofstraße 1, 60590 Frankfurt, Germany.
  • Müller-Tidow C; Department of Hematology and Oncology, University of Halle, Ernst-Grube-Street 40, 06120 Halle, Germany.
  • Kuchenbauer F; Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany.
  • Schütz E; Chronix Biomedical, Goetheallee 8, 37073 Göttingen, Germany.
  • Green AR; Department of Haematology, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK; Cambridge Institute for Medical Research, Wellcome Trust/MRC Stem Cell Institute, Cambridge CB2 0XY, UK.
  • Urlaub H; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany; Bioanalytics, Georg August University, Robert-Koch-Straße 40, 37073 Göttingen, Germany.
  • Stegmaier K; Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA 02115, USA; Broad Institute, Cambridge, MA 02142, USA.
  • Humphries RK; Terry Fox Laboratory, British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, BC V5Z 1L3, Canada; Department of Medicine, University of British Columbia, Vancouver, BC V5Z 1M9, Canada.
  • Serve H; Department of Medicine II, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany; German Cancer Research Center and German Cancer Consortium, 69120 Heidelberg, Germany.
  • Oellerich T; Department of Medicine II, Hematology/Oncology, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany; Department of Haematology, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK; Cambridge Institute for Medical Research, Wellcome Trust/MRC Stem Cell Institute, Cambridge CB2 0XY
Cancer Cell ; 31(4): 549-562.e11, 2017 04 10.
Article in En | MEDLINE | ID: mdl-28399410
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Homeodomain Proteins / MicroRNAs / Syk Kinase / Neoplasm Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Alemania Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Homeodomain Proteins / MicroRNAs / Syk Kinase / Neoplasm Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Alemania Country of publication: Estados Unidos