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Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines.
Klein, Christian; Waldhauer, Inja; Nicolini, Valeria G; Freimoser-Grundschober, Anne; Nayak, Tapan; Vugts, Danielle J; Dunn, Claire; Bolijn, Marije; Benz, Jörg; Stihle, Martine; Lang, Sabine; Roemmele, Michaele; Hofer, Thomas; van Puijenbroek, Erwin; Wittig, David; Moser, Samuel; Ast, Oliver; Brünker, Peter; Gorr, Ingo H; Neumann, Sebastian; de Vera Mudry, Maria Cristina; Hinton, Heather; Crameri, Flavio; Saro, Jose; Evers, Stefan; Gerdes, Christian; Bacac, Marina; van Dongen, Guus; Moessner, Ekkehard; Umaña, Pablo.
Affiliation
  • Klein C; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Waldhauer I; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Nicolini VG; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Freimoser-Grundschober A; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Nayak T; Roche Pharma Research & Early Development, Roche Innovation Center Basel , Basel, Switzerland.
  • Vugts DJ; Roche Pharma Research & Early Development, Department of Radiology & Nuclear Medicine, VU University Medical Center , Amsterdam, the Netherlands.
  • Dunn C; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Bolijn M; Roche Pharma Research & Early Development, Department of Radiology & Nuclear Medicine, VU University Medical Center , Amsterdam, the Netherlands.
  • Benz J; Roche Pharma Research & Early Development, Roche Innovation Center Basel , Basel, Switzerland.
  • Stihle M; Roche Pharma Research & Early Development, Roche Innovation Center Basel , Basel, Switzerland.
  • Lang S; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Roemmele M; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Hofer T; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • van Puijenbroek E; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Wittig D; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Moser S; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Ast O; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Brünker P; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Gorr IH; Roche Pharma Research & Early Development, Roche Innovation Center Munich , Penzberg, Germany.
  • Neumann S; Roche Pharma Research & Early Development, Roche Innovation Center Basel , Basel, Switzerland.
  • de Vera Mudry MC; Roche Pharma Research & Early Development, Roche Innovation Center Basel , Basel, Switzerland.
  • Hinton H; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Crameri F; Roche Pharma Research & Early Development, Roche Innovation Center Basel , Basel, Switzerland.
  • Saro J; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Evers S; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Gerdes C; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Bacac M; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • van Dongen G; Roche Pharma Research & Early Development, Department of Radiology & Nuclear Medicine, VU University Medical Center , Amsterdam, the Netherlands.
  • Moessner E; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
  • Umaña P; Roche Pharma Research & Early Development, Roche Innovation Center Zurich , Schlieren, Switzerland.
Oncoimmunology ; 6(3): e1277306, 2017.
Article in En | MEDLINE | ID: mdl-28405498
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Oncoimmunology Year: 2017 Document type: Article Affiliation country: Suiza
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Oncoimmunology Year: 2017 Document type: Article Affiliation country: Suiza