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Synthesis and biological evaluation of largazole zinc-binding group analogs.
Kim, Bumki; Ratnayake, Ranjala; Lee, Hyunji; Shi, Guqin; Zeller, Sabrina L; Li, Chenglong; Luesch, Hendrik; Hong, Jiyong.
Affiliation
  • Kim B; Department of Chemistry, Duke University, Durham, NC 27708, United States.
  • Ratnayake R; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32610, United States; Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, FL 32610, United States.
  • Lee H; Department of Chemistry, Duke University, Durham, NC 27708, United States.
  • Shi G; Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, United States.
  • Zeller SL; Department of Chemistry, Duke University, Durham, NC 27708, United States.
  • Li C; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32610, United States; Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, FL 32610, United States.
  • Luesch H; Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, FL 32610, United States; Center for Natural Products, Drug Discovery and Development (CNPD3), University of Florida, Gainesville, FL 32610, United States. Electronic address: luesch@cop.ufl.edu.
  • Hong J; Department of Chemistry, Duke University, Durham, NC 27708, United States; Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, United States. Electronic address: jiyong.hong@duke.edu.
Bioorg Med Chem ; 25(12): 3077-3086, 2017 06 15.
Article in En | MEDLINE | ID: mdl-28416100
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Zinc / Depsipeptides / Histone Deacetylase 1 / Histone Deacetylase Inhibitors Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2017 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Zinc / Depsipeptides / Histone Deacetylase 1 / Histone Deacetylase Inhibitors Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2017 Document type: Article Affiliation country: Estados Unidos Country of publication: Reino Unido