Update on the Notochord Including its Embryology, Molecular Development, and Pathology: A Primer for the Clinician.
Cureus
; 9(4): e1137, 2017 Apr 04.
Article
in En
| MEDLINE
| ID: mdl-28480155
ABSTRACT
The notochord is a rod-like embryological structure, which plays a vital role in the development of the vertebrate. Though embryological, remnants of this structure have been observed in the nucleus pulposus of the intervertebral discs of normal adults. Pathologically, these remnants can give rise to slow-growing and recurrent notochord-derived tumors called chordomas. Using standard search engines, the literature was reviewed regarding the anatomy, embryology, molecular development, and pathology of the human notochord. Clinicians who interpret imaging or treat patients with pathologies linked to the notochord should have a good working knowledge of its development and pathology.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Cureus
Year:
2017
Document type:
Article