Phytol induces ROS mediated apoptosis by induction of caspase 9 and 3 through activation of TRAIL, FAS and TNF receptors and inhibits tumor progression factor Glucose 6 phosphate dehydrogenase in lung carcinoma cell line (A549).

Thakor, Parth; Subramanian, Ramalingam B; Thakkar, Sampark S; Ray, Arabinda; Thakkar, Vasudev R

Thakor, Parth; Subramanian, Ramalingam B; Thakkar, Sampark S; Ray, Arabinda; Thakkar, Vasudev R.

Affiliation

Thakor P; P. G. Department of Biosciences, Sardar Patel Maidan, Bakrol-Vadtal Road, Satellite Campus, Bakrol, Sardar Patel University, Vallabhvidyanagar, India. Electronic address: parth7218@gmail.com.
Subramanian RB; P. G. Department of Biosciences, Sardar Patel Maidan, Bakrol-Vadtal Road, Satellite Campus, Bakrol, Sardar Patel University, Vallabhvidyanagar, India.
Thakkar SS; Department of Organic Chemistry, P. D. Patel Institute of Applied Sciences, Charotar University of Science and Technology, Changa, India.
Ray A; Department of Organic Chemistry, P. D. Patel Institute of Applied Sciences, Charotar University of Science and Technology, Changa, India.
Thakkar VR; P. G. Department of Biosciences, Sardar Patel Maidan, Bakrol-Vadtal Road, Satellite Campus, Bakrol, Sardar Patel University, Vallabhvidyanagar, India. Electronic address: vasuthakkar@gmail.com.

Biomed Pharmacother ; 92: 491-500, 2017 Aug.

Article in En | MEDLINE | ID: mdl-28575806

Subject(s)
Key words

Apoptosis; G6PD; Human lung carcinoma cells (A549); Phytol; ROS; TRAIL

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phytol / Reactive Oxygen Species / Caspase 3 / Caspase 9 / Glucosephosphate Dehydrogenase / Lung Neoplasms Limits: Humans Language: En Journal: Biomed Pharmacother Year: 2017 Document type: Article

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