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The pathogenic LRRK2 R1441C mutation induces specific deficits modeling the prodromal phase of Parkinson's disease in the mouse.
Giesert, F; Glasl, L; Zimprich, A; Ernst, L; Piccoli, G; Stautner, C; Zerle, J; Hölter, S M; Vogt Weisenhorn, D M; Wurst, W.
Affiliation
  • Giesert F; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany; Technische Universität München-Weihenstephan, Lehrstuhl für Entwicklungsgenetik, c/o Helmholtz Zentrum München, Ingolstädter Landstr. 1
  • Glasl L; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.
  • Zimprich A; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.
  • Ernst L; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.
  • Piccoli G; Center for Integrative Biology (CIBIO), University of Trento and Dulbecco Telethon Institute Trento, Italy.
  • Stautner C; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.
  • Zerle J; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.
  • Hölter SM; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.
  • Vogt Weisenhorn DM; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany; Technische Universität München-Weihenstephan, Lehrstuhl für Entwicklungsgenetik, c/o Helmholtz Zentrum München, Ingolstädter Landstr. 1
  • Wurst W; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany; Technische Universität München-Weihenstephan, Lehrstuhl für Entwicklungsgenetik, c/o Helmholtz Zentrum München, Ingolstädter Landstr. 1
Neurobiol Dis ; 105: 179-193, 2017 Sep.
Article in En | MEDLINE | ID: mdl-28576705
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Point Mutation / Prodromal Symptoms / Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2017 Document type: Article Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Point Mutation / Prodromal Symptoms / Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2017 Document type: Article Country of publication: Estados Unidos