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Visit-to-Visit Blood Pressure Variability and Alzheimer's Disease: Links and Risks.
Nagai, Michiaki; Dote, Keigo; Kato, Masaya; Sasaki, Shota; Oda, Noboru; Kagawa, Eisuke; Nakano, Yoshinori; Yamane, Aya; Higashihara, Tasuku; Miyauchi, Shunsuke; Tsuchiya, Akane.
Affiliation
  • Nagai M; Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
  • Dote K; Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
  • Kato M; Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
  • Sasaki S; Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
  • Oda N; Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
  • Kagawa E; Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
  • Nakano Y; Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
  • Yamane A; Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
  • Higashihara T; Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
  • Miyauchi S; Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
  • Tsuchiya A; Department of Cardiology, Hiroshima City Asa Hospital, Hiroshima, Japan.
J Alzheimers Dis ; 59(2): 515-526, 2017.
Article in En | MEDLINE | ID: mdl-28598842
While hypertension has been shown to be a risk factor for vascular dementia, several studies have also demonstrated that hypertension also increases the risk of Alzheimer's disease (AD). Although the relationship between visit-to-visit blood pressure variability (VVV) and cognitive impairment, including AD, have been provided, the mechanisms remain poorly understood. This review paper focuses on the relationship of VVV with AD and summarizes the pathophysiology underlying that relationship, which appears to be mediated by arterial stiffness.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Pressure / Alzheimer Disease / Cognitive Dysfunction / Hypertension Type of study: Etiology_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Alzheimers Dis Journal subject: GERIATRIA / NEUROLOGIA Year: 2017 Document type: Article Affiliation country: Japón Country of publication: Países Bajos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Blood Pressure / Alzheimer Disease / Cognitive Dysfunction / Hypertension Type of study: Etiology_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Alzheimers Dis Journal subject: GERIATRIA / NEUROLOGIA Year: 2017 Document type: Article Affiliation country: Japón Country of publication: Países Bajos