Morphology and Function of Meibomian Glands and Other Tear Film Parameters in Junior High School Students.
Cornea
; 36(8): 922-926, 2017 Aug.
Article
in En
| MEDLINE
| ID: mdl-28628504
ABSTRACT
PURPOSE:
We measured tear film parameters, including the morphology and function of meibomian glands, in junior high school students at 15 years of age.METHODS:
A total of 111 eyes of 111 students (56 males and 55 females) were enrolled in the study. The ocular symptom score (0-14), after-school study time, lipid layer thickness (LLT) of the tear film, partial blink rate, lid margin abnormalities (0-4), tear film breakup time, corneal and conjunctival epithelial damage (fluorescein staining score, 0-9), meiboscore as determined by noncontact meibography (0-6), Schirmer test value, and meibum grade (0-3) were determined. The relationships between parameters were evaluated with the Spearman correlation coefficient (ρ).RESULTS:
The meiboscore was 2.8 ± 1.2, and the meibum grade was 1.8 ± 1.2. The meiboscore significantly correlated with the meibum grade (ρ = 0.272, P = 0.004), Schirmer test value (ρ = -0.220, P = 0.021), and LLT (ρ = -0.264, P = 0.005). The breakup time significantly correlated with LLT (ρ = 0.261, P = 0.006), meibum grade (ρ = -0.338, P < 0.001), and fluorescein staining score (ρ = -0.214, P = 0.025). The partial blink rate significantly correlated with the Schirmer test value (ρ = -0.240, P = 0.011). The meiboscore (P < 0.001) and meibum grade (P = 0.032) were significantly greater in males than in females.CONCLUSIONS:
The morphology and function of meibomian glands are altered even at 15 years of age, with the changes being more prominent in males than in females.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Tears
/
Eyelids
/
Meibomian Glands
Type of study:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Female
/
Humans
/
Male
Language:
En
Journal:
Cornea
Year:
2017
Document type:
Article
Affiliation country:
Japón