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Dysregulated Zn2+ homeostasis impairs cardiac type-2 ryanodine receptor and mitsugumin 23 functions, leading to sarcoplasmic reticulum Ca2+ leakage.
Reilly-O'Donnell, Benedict; Robertson, Gavin B; Karumbi, Angela; McIntyre, Connor; Bal, Wojciech; Nishi, Miyuki; Takeshima, Hiroshi; Stewart, Alan J; Pitt, Samantha J.
Affiliation
  • Reilly-O'Donnell B; From the School of Medicine, University of St. Andrews, St. Andrews, KY16 9TF, Scotland, United Kingdom.
  • Robertson GB; From the School of Medicine, University of St. Andrews, St. Andrews, KY16 9TF, Scotland, United Kingdom.
  • Karumbi A; From the School of Medicine, University of St. Andrews, St. Andrews, KY16 9TF, Scotland, United Kingdom.
  • McIntyre C; From the School of Medicine, University of St. Andrews, St. Andrews, KY16 9TF, Scotland, United Kingdom.
  • Bal W; Department of Biophysics, Institute of Biochemistry and Biophysics, Polish Academy of Science, Warsaw, 02-106 Poland, and.
  • Nishi M; Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan.
  • Takeshima H; Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan.
  • Stewart AJ; From the School of Medicine, University of St. Andrews, St. Andrews, KY16 9TF, Scotland, United Kingdom.
  • Pitt SJ; From the School of Medicine, University of St. Andrews, St. Andrews, KY16 9TF, Scotland, United Kingdom, sjp24@st-andrews.ac.uk.
J Biol Chem ; 292(32): 13361-13373, 2017 08 11.
Article in En | MEDLINE | ID: mdl-28630041
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoplasmic Reticulum / Zinc / Ryanodine Receptor Calcium Release Channel / Calcium Signaling / Myocytes, Cardiac / Membrane Proteins Limits: Animals Language: En Journal: J Biol Chem Year: 2017 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sarcoplasmic Reticulum / Zinc / Ryanodine Receptor Calcium Release Channel / Calcium Signaling / Myocytes, Cardiac / Membrane Proteins Limits: Animals Language: En Journal: J Biol Chem Year: 2017 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos