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Long-term enzyme replacement therapy improves neurocognitive functioning and hippocampal synaptic plasticity in immune-tolerant alpha-mannosidosis mice.
Stroobants, Stijn; Damme, Markus; Van der Jeugd, Ann; Vermaercke, Ben; Andersson, Claes; Fogh, Jens; Saftig, Paul; Blanz, Judith; D'Hooge, Rudi.
Affiliation
  • Stroobants S; Laboratory of Biological Psychology, KU Leuven, Tiensestraat 102, 3000 Leuven, Belgium. Electronic address: stijn.stroobants@ppw.kuleuven.be.
  • Damme M; Institute of Biochemistry, University of Kiel, Olshausenstrasse 40, 24098 Kiel, Germany. Electronic address: mdamme@biochem.uni-kiel.de.
  • Van der Jeugd A; Laboratory of Biological Psychology, KU Leuven, Tiensestraat 102, 3000 Leuven, Belgium. Electronic address: ann.vanderjeugd@ppw.kuleuven.be.
  • Vermaercke B; Laboratory of Biological Psychology, KU Leuven, Tiensestraat 102, 3000 Leuven, Belgium. Electronic address: ben.vermaercke@ppw.kuleuven.be.
  • Andersson C; Zymenex A/S, Roskildevej 12C, 3400 Hillerød, Denmark. Electronic address: ca@zymenex.com.
  • Fogh J; Zymenex A/S, Roskildevej 12C, 3400 Hillerød, Denmark. Electronic address: jf@zymenex.com.
  • Saftig P; Institute of Biochemistry, University of Kiel, Olshausenstrasse 40, 24098 Kiel, Germany. Electronic address: psaftig@biochem.uni-kiel.de.
  • Blanz J; Institute of Biochemistry, University of Kiel, Olshausenstrasse 40, 24098 Kiel, Germany. Electronic address: jblanz@biochem.uni-kiel.de.
  • D'Hooge R; Laboratory of Biological Psychology, KU Leuven, Tiensestraat 102, 3000 Leuven, Belgium. Electronic address: rudi.dhooge@ppw.kuleuven.be.
Neurobiol Dis ; 106: 255-268, 2017 Oct.
Article in En | MEDLINE | ID: mdl-28720484
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Cognition / Enzyme Replacement Therapy / Hippocampus / Alpha-Mannosidosis / Neuronal Plasticity Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2017 Document type: Article Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Cognition / Enzyme Replacement Therapy / Hippocampus / Alpha-Mannosidosis / Neuronal Plasticity Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2017 Document type: Article Country of publication: Estados Unidos