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Activation of ALDH1A1 in MDA-MB-468 breast cancer cells that over-express CYP2J2 protects against paclitaxel-dependent cell death mediated by reactive oxygen species.
Allison, Sarah E; Chen, Yongjuan; Petrovic, Nenad; Zhang, Jian; Bourget, Kirsi; Mackenzie, Peter I; Murray, Michael.
Affiliation
  • Allison SE; Pharmacogenomics and Drug Development Group, Discipline of Pharmacology, University of Sydney, NSW 2006, Australia.
  • Chen Y; Pharmacogenomics and Drug Development Group, Discipline of Pharmacology, University of Sydney, NSW 2006, Australia.
  • Petrovic N; School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide, SA 5001, Australia.
  • Zhang J; Pharmacogenomics and Drug Development Group, Discipline of Pharmacology, University of Sydney, NSW 2006, Australia.
  • Bourget K; Pharmacogenomics and Drug Development Group, Discipline of Pharmacology, University of Sydney, NSW 2006, Australia.
  • Mackenzie PI; Clinical Pharmacology, Flinders University of South Australia, Bedford Park, SA 5042, Australia.
  • Murray M; Pharmacogenomics and Drug Development Group, Discipline of Pharmacology, University of Sydney, NSW 2006, Australia. Electronic address: michael.murray@sydney.edu.au.
Biochem Pharmacol ; 143: 79-89, 2017 11 01.
Article in En | MEDLINE | ID: mdl-28756208
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Paclitaxel / Reactive Oxygen Species / Apoptosis / Cytochrome P-450 Enzyme System / Aldehyde Dehydrogenase / Antineoplastic Agents, Phytogenic Limits: Female / Humans Language: En Journal: Biochem Pharmacol Year: 2017 Document type: Article Affiliation country: Australia Country of publication: Reino Unido
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Paclitaxel / Reactive Oxygen Species / Apoptosis / Cytochrome P-450 Enzyme System / Aldehyde Dehydrogenase / Antineoplastic Agents, Phytogenic Limits: Female / Humans Language: En Journal: Biochem Pharmacol Year: 2017 Document type: Article Affiliation country: Australia Country of publication: Reino Unido