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Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients.
Schonhoft, Joseph D; Monteiro, Cecilia; Plate, Lars; Eisele, Yvonne S; Kelly, John M; Boland, Daniel; Parker, Christopher G; Cravatt, Benjamin F; Teruya, Sergio; Helmke, Stephen; Maurer, Mathew; Berk, John; Sekijima, Yoshiki; Novais, Marta; Coelho, Teresa; Powers, Evan T; Kelly, Jeffery W.
Affiliation
  • Schonhoft JD; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Monteiro C; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Plate L; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Eisele YS; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Kelly JM; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Boland D; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Parker CG; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Cravatt BF; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Teruya S; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Helmke S; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Maurer M; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Berk J; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Sekijima Y; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Novais M; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
  • Coelho T; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Powers ET; The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Kelly JW; Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
Sci Transl Med ; 9(407)2017 Sep 13.
Article in En | MEDLINE | ID: mdl-28904227

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Prealbumin / Molecular Probes / Protein Folding / Amyloidosis, Familial / Protein Multimerization Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2017 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Prealbumin / Molecular Probes / Protein Folding / Amyloidosis, Familial / Protein Multimerization Type of study: Observational_studies / Risk_factors_studies Limits: Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2017 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos