Human Immunodeficiency Virus and Aging in the Era of Effective Antiretroviral Therapy.

Van Epps, Puja; Kalayjian, Robert C

Van Epps, Puja; Kalayjian, Robert C.

Affiliation

Van Epps P; Division of Infectious Diseases, Geriatric Research, Education, and Clinical Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Case Western Reserve University School of Medicine, 10701 East Boulevard, Cleveland, OH 44106, USA. Electronic address: puja.vanepps@va.gov.
Kalayjian RC; Division of Infectious Diseases, Geriatric Research, Education, and Clinical Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Case Western Reserve University School of Medicine, 10701 East Boulevard, Cleveland, OH 44106, USA; Division of Infectious Diseases, MetroHealth Medical Center, Case Western Reserve University School of Medicine, 2500 MetroHealth Drive, Cleveland, OH 44109, USA.

Infect Dis Clin North Am ; 31(4): 791-810, 2017 12.

Article in En | MEDLINE | ID: mdl-28916384

ABSTRACT

ABSTRACT

Persons living with HIV (PLWH) have accentuated risks for age-associated comorbidities. Compared to the general population, PLWH have a 2-fold higher risk of cardiovascular disease, a 3-fold increased risk of fracture, and a risk of kidney disease that is comparable to that in diabetes. Some comorbidities may present at younger ages than among the general population, suggesting the possibility of accelerated aging with HIV infection.

Subject(s)
Key words

Aging; Comorbidities; Frailty; HIV; Senescence; Telomere

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aging / HIV Infections / Anti-Retroviral Agents Type of study: Etiology_studies / Risk_factors_studies Limits: Aged / Humans Language: En Journal: Infect Dis Clin North Am Journal subject: DOENCAS TRANSMISSIVEIS Year: 2017 Document type: Article

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