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Quantitative target proteomics of chromosome 13 human blood plasma proteins.
Kopylov, A T; Ilgisonis, E V; Tikhonova, O V; Farafonova, T E; Novikova, S E; Zgoda, V G; Ponomarenko, E A; Lisitsa, A V; Markin, A A; Morukov, B V; Grigoriev, A I; Archakov, A I.
Affiliation
  • Kopylov AT; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia.
  • Ilgisonis EV; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia.
  • Tikhonova OV; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia.
  • Farafonova TE; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia.
  • Novikova SE; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia.
  • Zgoda VG; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia. vic@ibmh.msk.su.
  • Ponomarenko EA; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia.
  • Lisitsa AV; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia.
  • Markin AA; Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, 123007, Russia.
  • Morukov BV; Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, 123007, Russia.
  • Grigoriev AI; Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, 123007, Russia.
  • Archakov AI; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia.
Dokl Biochem Biophys ; 476(1): 326-328, 2017 Sep.
Article in En | MEDLINE | ID: mdl-29101746
ABSTRACT
Quantitative proteomic analysis of 50 blood plasma samples of healthy volunteers who underwent a comprehensive medical examination and were found eligible for space flights was performed. As a result of directed mass spectrometric analysis, signals for 128 proteins, which accounted for nearly 40% of the total number of chromosome 13 gene products, were detected. The analysis of interindividual variation of concentrations of chromosome 13 proteins showed the presence of a pool comprising 41 proteins with a low variation (CV < 30%), which can potentially be used as biomarkers.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromosomes, Human, Pair 13 / Blood Proteins / Proteomics Limits: Humans Language: En Journal: Dokl Biochem Biophys Journal subject: BIOFISICA / BIOQUIMICA Year: 2017 Document type: Article Affiliation country: Rusia
Fulltext
Add to My VHL
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromosomes, Human, Pair 13 / Blood Proteins / Proteomics Limits: Humans Language: En Journal: Dokl Biochem Biophys Journal subject: BIOFISICA / BIOQUIMICA Year: 2017 Document type: Article Affiliation country: Rusia