G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.
EMBO Mol Med
; 10(1): 22-31, 2018 01.
Article
in En
| MEDLINE
| ID: mdl-29113975
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Small Molecule Libraries
/
G-Quadruplexes
/
Drug Discovery
/
Frontotemporal Dementia
/
C9orf72 Protein
/
Amyotrophic Lateral Sclerosis
Type of study:
Prognostic_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
EMBO Mol Med
Journal subject:
BIOLOGIA MOLECULAR
Year:
2018
Document type:
Article
Affiliation country:
Reino Unido
Country of publication:
Reino Unido