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Development and validation of an LC-MS/MS method for the determination of a novel thienoquinolin urea transporter inhibitor PU-48 in rat plasma and its application to a pharmacokinetic study.
Zhang, Zhi-Yuan; Wang, Xin; Liu, Dan; Zhang, Hua; Zhang, Qiang; Lu, Ying-Yuan; Li, Pu; Lou, Ya-Qing; Yang, Bao-Xue; Lu, Chuang; Lou, Ya-Xin; Zhang, Guo-Liang.
Affiliation
  • Zhang ZY; Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Wang X; Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Liu D; Proteomics Laboratory, Medical and Health Analysis Center, Peking University, Beijing, China.
  • Zhang H; Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, China.
  • Zhang Q; Department of Pharmaceutics, School of Pharmaceutical Sciences, Peking University, Beijing, China.
  • Lu YY; Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Li P; Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Lou YQ; Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Yang BX; Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Lu C; Department of Drug Metabolism and Pharmacokinetics, Biogen, Cambridge, Massachusetts, USA.
  • Lou YX; Proteomics Laboratory, Medical and Health Analysis Center, Peking University, Beijing, China.
  • Zhang GL; Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
Biomed Chromatogr ; 32(4)2018 Apr.
Article in En | MEDLINE | ID: mdl-29193233
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Transport Proteins / Quinolines / Carrier Proteins / Chromatography, Liquid / Enzyme Inhibitors / Tandem Mass Spectrometry Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Biomed Chromatogr Year: 2018 Document type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Transport Proteins / Quinolines / Carrier Proteins / Chromatography, Liquid / Enzyme Inhibitors / Tandem Mass Spectrometry Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Biomed Chromatogr Year: 2018 Document type: Article Affiliation country: China