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Inhibition of Orai1-mediated Ca2+ entry limits endothelial cell inflammation by suppressing calcineurin-NFATc4 signaling pathway.
Yu, Bei-Xin; Yuan, Jia-Ni; Zhang, Fei-Ran; Liu, Ying-Ying; Zhang, Ting-Ting; Li, Kai; Lv, Xiao-Fei; Zhou, Jia-Guo; Huang, Lin-Yan; Shang, Jin-Yan; Liang, Si-Jia.
Affiliation
  • Yu BX; Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Guangzhou, China; Center for Translational Medicine, The First Affiliated Hospital, Guangzhou, China.
  • Yuan JN; Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Guangzhou, China.
  • Zhang FR; Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Guangzhou, China.
  • Liu YY; Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Guangzhou, China.
  • Zhang TT; Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Guangzhou, China.
  • Li K; Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Guangzhou, China.
  • Lv XF; Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Guangzhou, China.
  • Zhou JG; Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Guangzhou, China; Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangzhou, China; Key Laboratory of Cardiovascular Diseases, School of Basic Medical
  • Huang LY; School of Medical Technology, Xuzhou Medical University, Xuzhou, China.
  • Shang JY; Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Guangzhou, China. Electronic address: jinyan_shang1988@163.com.
  • Liang SJ; Department of Pharmacology, Cardiac and Cerebral Vascular Research Center, Zhongshan School of Medicine, Guangzhou, China. Electronic address: liangsj5@mail.sysu.edu.cn.
Biochem Biophys Res Commun ; 495(2): 1864-1870, 2018 01 08.
Article in En | MEDLINE | ID: mdl-29225169
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortitis / Endothelium, Vascular / Cell Adhesion Molecules / Calcium / Calcineurin / NFATC Transcription Factors / ORAI1 Protein Limits: Animals / Humans Language: En Journal: Biochem Biophys Res Commun Year: 2018 Document type: Article Affiliation country: China Country of publication: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortitis / Endothelium, Vascular / Cell Adhesion Molecules / Calcium / Calcineurin / NFATC Transcription Factors / ORAI1 Protein Limits: Animals / Humans Language: En Journal: Biochem Biophys Res Commun Year: 2018 Document type: Article Affiliation country: China Country of publication: Estados Unidos