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Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib.
Gong, Xueqian; Litchfield, Lacey M; Webster, Yue; Chio, Li-Chun; Wong, Swee Seong; Stewart, Trent R; Dowless, Michele; Dempsey, Jack; Zeng, Yi; Torres, Raquel; Boehnke, Karsten; Mur, Cecilia; Marugán, Carlos; Baquero, Carmen; Yu, Chunping; Bray, Steven M; Wulur, Isabella H; Bi, Chen; Chu, Shaoyou; Qian, Hui-Rong; Iversen, Philip W; Merzoug, Farhana F; Ye, Xiang S; Reinhard, Christoph; De Dios, Alfonso; Du, Jian; Caldwell, Charles W; Lallena, María José; Beckmann, Richard P; Buchanan, Sean G.
Affiliation
  • Gong X; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Litchfield LM; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Webster Y; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Chio LC; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Wong SS; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Stewart TR; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Dowless M; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Dempsey J; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Zeng Y; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Torres R; Eli Lilly and Company, Alcobendas, Madrid, Spain.
  • Boehnke K; Eli Lilly and Company, Alcobendas, Madrid, Spain.
  • Mur C; Eli Lilly and Company, Alcobendas, Madrid, Spain.
  • Marugán C; Eli Lilly and Company, Alcobendas, Madrid, Spain.
  • Baquero C; Eli Lilly and Company, Alcobendas, Madrid, Spain.
  • Yu C; Eli Lilly and Company, Shanghai, China.
  • Bray SM; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Wulur IH; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Bi C; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Chu S; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Qian HR; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Iversen PW; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Merzoug FF; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Ye XS; Eli Lilly and Company, Shanghai, China.
  • Reinhard C; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • De Dios A; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Du J; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Caldwell CW; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Lallena MJ; Eli Lilly and Company, Alcobendas, Madrid, Spain.
  • Beckmann RP; Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Buchanan SG; Eli Lilly and Company, Indianapolis, IN 46285, USA. Electronic address: buchananse@lilly.com.
Cancer Cell ; 32(6): 761-776.e6, 2017 Dec 11.
Article in En | MEDLINE | ID: mdl-29232554
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Cyclin D / Aminopyridines / Neoplasms Type of study: Diagnostic_studies / Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Cyclin D / Aminopyridines / Neoplasms Type of study: Diagnostic_studies / Risk_factors_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Cell Journal subject: NEOPLASIAS Year: 2017 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos