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Atorvastatin exerts inhibitory effect on endothelial senescence in hyperlipidemic rats through a mechanism involving down-regulation of miR-21-5p/203a-3p.
Zhang, Jie-Jie; Zhang, Yin-Zhuang; Peng, Jing-Jie; Li, Nian-Sheng; Xiong, Xiao-Ming; Ma, Qi-Lin; Luo, Xiu-Ju; Liu, Bin; Peng, Jun.
Affiliation
  • Zhang JJ; Department of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, China; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
  • Zhang YZ; Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
  • Peng JJ; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
  • Li NS; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
  • Xiong XM; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China.
  • Ma QL; Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha 410008, China.
  • Luo XJ; Department of Laboratory Medicine, Xiangya School of Medicine, Central South University, Changsha 410013, China.
  • Liu B; Department of Pharmacy, Xiangya Hospital, Central South University, Changsha 410008, China. Electronic address: liubin@csu.edu.cn.
  • Peng J; Department of Pharmacology, School of Pharmaceutical Sciences, Central South University, Changsha 410078, China. Electronic address: Junpeng@csu.edu.cn.
Mech Ageing Dev ; 169: 10-18, 2018 01.
Article in En | MEDLINE | ID: mdl-29248491
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aorta / Down-Regulation / Cellular Senescence / MicroRNAs / Endothelial Cells / Atorvastatin / Hyperlipidemias Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mech Ageing Dev Year: 2018 Document type: Article Affiliation country: China Country of publication: Irlanda
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aorta / Down-Regulation / Cellular Senescence / MicroRNAs / Endothelial Cells / Atorvastatin / Hyperlipidemias Type of study: Prognostic_studies Limits: Animals Language: En Journal: Mech Ageing Dev Year: 2018 Document type: Article Affiliation country: China Country of publication: Irlanda