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GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death.
Sieber, Jonas; Wieder, Nicolas; Clark, Abbe; Reitberger, Manuel; Matan, Sofia; Schoenfelder, Jeannine; Zhang, Jianming; Mandinova, Anna; Bittker, Joshua Adam; Gutierrez, Juan; Aygün, Ozan; Udeshi, Namrata; Carr, Steven; Mundel, Peter; Jehle, Andreas Werner; Greka, Anna.
Affiliation
  • Sieber J; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Wieder N; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Clark A; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Reitberger M; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Matan S; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Schoenfelder J; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Zhang J; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Mandinova A; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Bittker JA; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Gutierrez J; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Aygün O; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Udeshi N; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Carr S; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Mundel P; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA.
  • Jehle AW; Department of Biomedicine, Molecular Nephrology, University of Basel, Basel 4031, Switzerland.
  • Greka A; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address: agreka@bwh.harvard.edu.
Cell Chem Biol ; 25(2): 175-184.e4, 2018 02 15.
Article in En | MEDLINE | ID: mdl-29249695
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Podocytes / Indenes / Kidney Diseases Limits: Humans Language: En Journal: Cell Chem Biol Year: 2018 Document type: Article Affiliation country: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Podocytes / Indenes / Kidney Diseases Limits: Humans Language: En Journal: Cell Chem Biol Year: 2018 Document type: Article Affiliation country: Estados Unidos