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Characterization of KPC-Encoding Plasmids from Enterobacteriaceae Isolated in a Czech Hospital.
Kukla, Rudolf; Chudejova, Katerina; Papagiannitsis, Costas C; Medvecky, Matej; Habalova, Katerina; Hobzova, Lenka; Bolehovska, Radka; Pliskova, Lenka; Hrabak, Jaroslav; Zemlickova, Helena.
Affiliation
  • Kukla R; Department of Clinical Microbiology, University Hospital and Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
  • Chudejova K; Department of Microbiology, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic.
  • Papagiannitsis CC; Biomedical Center, Faculty of Medicine, Charles University, Pilsen, Czech Republic.
  • Medvecky M; Department of Clinical Microbiology, University Hospital and Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic c.papagiannitsis@gmail.com.
  • Habalova K; Department of Microbiology, Faculty of Medicine and University Hospital in Pilsen, Charles University, Pilsen, Czech Republic.
  • Hobzova L; Biomedical Center, Faculty of Medicine, Charles University, Pilsen, Czech Republic.
  • Bolehovska R; Veterinary Research Institute, Brno, Czech Republic.
  • Pliskova L; National Centre for Biomolecular Research, Faculty of Science, Masaryk University, Brno, Czech Republic.
  • Hrabak J; Department of Clinical Microbiology, University Hospital and Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic.
  • Zemlickova H; Department of Hospital Hygiene, University Hospital, Hradec Kralove, Czech Republic.
Antimicrob Agents Chemother ; 62(3)2018 03.
Article in En | MEDLINE | ID: mdl-29263065
ABSTRACT
Ten Enterobacteriaceae isolates collected in a Czech hospital carried blaKPC-positive plasmids of different sizes (∼30, ∼45, and ∼80 kb). Sequencing revealed three types of plasmids (A to C) with the Tn4401a transposon. Type A plasmids comprised an IncR backbone and a KPC-2-encoding multidrug resistance (MDR) region. Type B plasmids were derivatives of type A plasmids carrying an IncN3-like segment, while type C plasmids were IncP6 plasmids sharing the same KPC-2-encoding MDR region with type A and B plasmids.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmids / Beta-Lactamases / Citrobacter freundii / Morganella morganii / Escherichia coli / Klebsiella pneumoniae Country/Region as subject: Europa Language: En Journal: Antimicrob Agents Chemother Year: 2018 Document type: Article Affiliation country: República Checa
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmids / Beta-Lactamases / Citrobacter freundii / Morganella morganii / Escherichia coli / Klebsiella pneumoniae Country/Region as subject: Europa Language: En Journal: Antimicrob Agents Chemother Year: 2018 Document type: Article Affiliation country: República Checa