Your browser doesn't support javascript.
loading
Frontal activity measured by near-infrared spectroscopy in patients taking different atypical antipsychotic drugs: A cross-sectional study.
Kono, Soichi; Miura, Itaru; Oshima, Sachie; Hikita, Masayuki; Wada, Akira; Suzuki, Rieko; Niwa, Shin-Ichi; Yabe, Hirooki.
Affiliation
  • Kono S; Department of Neuropsychiatry, Fukushima Medical University, Fukushima, Japan; Department of Psychiatry, Jusendo Shonan Hospital, Fukushima, Japan. Electronic address: papilk-no@diary.ocn.ne.jp.
  • Miura I; Department of Neuropsychiatry, Fukushima Medical University, Fukushima, Japan.
  • Oshima S; Department of Neuropsychiatry, Fukushima Medical University, Fukushima, Japan.
  • Hikita M; Department of Neuropsychiatry, Fukushima Medical University, Fukushima, Japan.
  • Wada A; Department of Neuropsychiatry, Fukushima Medical University, Fukushima, Japan; Department of Neuropsychiatry, The University of Tokyo Hospital, Tokyo, Japan.
  • Suzuki R; Department of Neuropsychiatry, Fukushima Medical University, Fukushima, Japan; Department of Psychiatry, Asaka Hospital, Fukushima, Japan.
  • Niwa SI; Department of Neuropsychiatry, Fukushima Medical University, Fukushima, Japan; Department of Psychiatry, Aizu Medical Center, Fukushima Medical University, Fukushima, Japan.
  • Yabe H; Department of Neuropsychiatry, Fukushima Medical University, Fukushima, Japan.
Psychiatry Res Neuroimaging ; 273: 42-45, 2018 03 30.
Article in En | MEDLINE | ID: mdl-29329742
ABSTRACT
Using near-infrared spectroscopy, we examined changes in the concentration of oxygenated hemoglobin ([oxy-Hb]) in the frontal lobe during a verbal fluency task in 20 patients with schizophrenia (10 patients each receiving olanzapine [OLZ] and risperidone [RIS]) and 10 healthy controls. We found that [oxy-Hb] levels in the prefrontal region were higher in the patients receiving OLZ than in those receiving RIS. These results suggest that antipsychotic drugs have different effects on cerebral hemodynamic patterns, which may reflect frontal lobe function. Further studies with a larger sample size are needed to verify our preliminary findings.
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Antipsychotic Agents / Risperidone / Olanzapine / Frontal Lobe Type of study: Observational_studies / Prevalence_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: Psychiatry Res Neuroimaging Year: 2018 Document type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Antipsychotic Agents / Risperidone / Olanzapine / Frontal Lobe Type of study: Observational_studies / Prevalence_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male Language: En Journal: Psychiatry Res Neuroimaging Year: 2018 Document type: Article