Activation-Induced Cytidine Deaminase Aided In Vitro Antibody Evolution.

An, Lili; Chen, Chuan; Luo, Ruiqi; Zhao, Yun; Hang, Haiying

An, Lili; Chen, Chuan; Luo, Ruiqi; Zhao, Yun; Hang, Haiying.

Affiliation

An L; Key Laboratory for Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing, 100101, China.
Chen C; Key Laboratory for Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing, 100101, China.
Luo R; Key Laboratory for Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing, 100101, China.
Zhao Y; Key Laboratory for Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing, 100101, China.
Hang H; Key Laboratory for Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing, 100101, China. hh91@sun5.ibp.ac.cn.

Methods Mol Biol ; 1707: 1-14, 2018.

Article in En | MEDLINE | ID: mdl-29388096

Subject(s)
Key words

Activation-induced cytidine deaminase (AID); Affinity maturation; Antibody evolution; Somatic hypermutation (SHM)

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transfection / Directed Molecular Evolution / Cytidine Deaminase / Antibodies, Monoclonal Limits: Animals / Humans Language: En Journal: Methods Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2018 Document type: Article Affiliation country: China Country of publication: Estados Unidos

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