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Organoids with cancer stem cell-like properties secrete exosomes and HSP90 in a 3D nanoenvironment.
Eguchi, Takanori; Sogawa, Chiharu; Okusha, Yuka; Uchibe, Kenta; Iinuma, Ryosuke; Ono, Kisho; Nakano, Keisuke; Murakami, Jun; Itoh, Manabu; Arai, Kazuya; Fujiwara, Toshifumi; Namba, Yuri; Murata, Yoshiki; Ohyama, Kazumi; Shimomura, Manami; Okamura, Hirohiko; Takigawa, Masaharu; Nakatsura, Tetsuya; Kozaki, Ken-Ichi; Okamoto, Kuniaki; Calderwood, Stuart K.
Affiliation
  • Eguchi T; Department of Dental Pharmacology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
  • Sogawa C; Advanced Research Center for Oral and Craniofacial Sciences, Okayama University Dental School, Okayama, Japan.
  • Okusha Y; Department of Dental Pharmacology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
  • Uchibe K; Department of Dental Pharmacology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
  • Iinuma R; Department of Oral Morphology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
  • Ono K; JSR Life Sciences Corporation, Tsukuba, Japan.
  • Nakano K; Department of Dental Pharmacology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
  • Murakami J; Advanced Research Center for Oral and Craniofacial Sciences, Okayama University Dental School, Okayama, Japan.
  • Itoh M; Department of Oral Pathology and Medicine, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
  • Arai K; Advanced Research Center for Oral and Craniofacial Sciences, Okayama University Dental School, Okayama, Japan.
  • Fujiwara T; Department of Oral Diagnosis and Dent-maxillofacial Radiology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
  • Namba Y; JSR Life Sciences Corporation, Tsukuba, Japan.
  • Murata Y; JSR Life Sciences Corporation, Tsukuba, Japan.
  • Ohyama K; Department of Dental Pharmacology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
  • Shimomura M; Department of Dental Pharmacology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
  • Okamura H; Department of Dental Pharmacology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
  • Takigawa M; Radio Isotope Research Center, Okayama University Dental School, Okayama, Japan.
  • Nakatsura T; Division of Cancer Immunotherapy, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.
  • Kozaki KI; Department of Oral Morphology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan.
  • Okamoto K; Advanced Research Center for Oral and Craniofacial Sciences, Okayama University Dental School, Okayama, Japan.
  • Calderwood SK; Division of Cancer Immunotherapy, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Japan.
PLoS One ; 13(2): e0191109, 2018.
Article in En | MEDLINE | ID: mdl-29415026
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Organoids / HSP90 Heat-Shock Proteins / Nanotechnology / Exosomes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2018 Document type: Article Affiliation country: Japón Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Neoplastic Stem Cells / Organoids / HSP90 Heat-Shock Proteins / Nanotechnology / Exosomes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2018 Document type: Article Affiliation country: Japón Country of publication: Estados Unidos