Sputum smear-positive, culture-negative state during anti-tuberculosis treatment in the MGIT liquid culture era.
Int J Tuberc Lung Dis
; 22(3): 306-308, 2018 03 01.
Article
in En
| MEDLINE
| ID: mdl-29471909
ABSTRACT
The sputum smear-positive, culture-negative state poses a challenge for clinicians. Previous studies have shown that most samples with positive smears during the later stages of treatment are culture-negative. Earlier studies generally used solid culture media, which tend to be less sensitive than current liquid culture systems. We examined the smear-positive, culture-negative state in the era of MGIT™ 960™ liquid cultures. We found that the smear-positive, culture-negative state occurred less frequently with MGIT culture, and that the majority of the samples with late positive smears were culture-negative, regardless of media type.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sputum
/
Tuberculosis, Pulmonary
/
Bacteriological Techniques
/
Mycobacterium tuberculosis
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Humans
Language:
En
Journal:
Int J Tuberc Lung Dis
Year:
2018
Document type:
Article
Affiliation country:
Estados Unidos