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Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition.
Jones, Douglas S; Jenney, Anne P; Joughin, Brian A; Sorger, Peter K; Lauffenburger, Douglas A.
Affiliation
  • Jones DS; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Jenney AP; Laboratory of Systems Pharmacology, Library of Integrated Network-based Cellular Signatures Center, Harvard Medical School, Boston, MA 02115, USA.
  • Joughin BA; Laboratory of Systems Pharmacology, Library of Integrated Network-based Cellular Signatures Center, Harvard Medical School, Boston, MA 02115, USA.
  • Sorger PK; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Lauffenburger DA; Koch Institute for Integrative Cancer Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Sci Signal ; 11(520)2018 03 06.
Article in En | MEDLINE | ID: mdl-29511118

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Synovial Fluid / Signal Transduction / P38 Mitogen-Activated Protein Kinases / Fibroblasts Limits: Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2018 Document type: Article Affiliation country: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Rheumatoid / Synovial Fluid / Signal Transduction / P38 Mitogen-Activated Protein Kinases / Fibroblasts Limits: Humans Language: En Journal: Sci Signal Journal subject: CIENCIA / FISIOLOGIA Year: 2018 Document type: Article Affiliation country: Estados Unidos