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Exosomal αvß6 integrin is required for monocyte M2 polarization in prostate cancer.
Lu, Huimin; Bowler, Nicholas; Harshyne, Larry A; Craig Hooper, D; Krishn, Shiv Ram; Kurtoglu, Senem; Fedele, Carmine; Liu, Qin; Tang, Hsin-Yao; Kossenkov, Andrew V; Kelly, William K; Wang, Kerith; Kean, Rhonda B; Weinreb, Paul H; Yu, Lei; Dutta, Anindita; Fortina, Paolo; Ertel, Adam; Stanczak, Maria; Forsberg, Flemming; Gabrilovich, Dmitry I; Speicher, David W; Altieri, Dario C; Languino, Lucia R.
Affiliation
  • Lu H; Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Bowler N; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Harshyne LA; Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Craig Hooper D; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Krishn SR; Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Kurtoglu S; Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Fedele C; Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Liu Q; Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, PA, USA.
  • Tang HY; Center for Systems and Computational Biology, Wistar Institute, Philadelphia, PA, USA.
  • Kossenkov AV; Center for Systems and Computational Biology, Wistar Institute, Philadelphia, PA, USA.
  • Kelly WK; Departments of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.
  • Wang K; Departments of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.
  • Kean RB; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Weinreb PH; Biogen Idec Inc., Cambridge, MA, USA.
  • Yu L; Flow Cytometry Core Facility, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.
  • Dutta A; Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
  • Fortina P; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Cancer Genomics and Bioinformatics Laboratory, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.
  • Ertel A; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Cancer Genomics and Bioinformatics Laboratory, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.
  • Stanczak M; Department of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Forsberg F; Department of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.
  • Gabrilovich DI; Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Immunology, Microenvironment and Metastasis Program, Wistar Institute, Philadelphia, PA, USA.
  • Speicher DW; Molecular and Cellular Oncogenesis Program, Wistar Institute, Philadelphia, PA, USA; Center for Systems and Computational Biology, Wistar Institute, Philadelphia, PA, USA.
  • Altieri DC; Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Immunology, Microenvironment and Metastasis Program, Wistar Institute, Philadelphia, PA, USA.
  • Languino LR; Prostate Cancer Discovery and Development Program, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. Electronic address: Lucia.Languino@jefferson.edu.
Matrix Biol ; 70: 20-35, 2018 09.
Article in En | MEDLINE | ID: mdl-29530483
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Adenocarcinoma / Gene Expression Regulation, Neoplastic / Integrins / STAT1 Transcription Factor / Exosomes / Antigens, Neoplasm Type of study: Prognostic_studies Language: En Journal: Matrix Biol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2018 Document type: Article Affiliation country: Estados Unidos
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Adenocarcinoma / Gene Expression Regulation, Neoplastic / Integrins / STAT1 Transcription Factor / Exosomes / Antigens, Neoplasm Type of study: Prognostic_studies Language: En Journal: Matrix Biol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2018 Document type: Article Affiliation country: Estados Unidos