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Regioselectivity significantly impacts microsomal glucuronidation efficiency of R/S-6, 7-, and 8-hydroxywarfarin.
Kim, So-Young; Jones, Drew R; Kang, Ji-Yeon; Yun, Chul-Ho; Miller, Grover P.
Affiliation
  • Kim SY; a School of Biological Sciences and Technology , Chonnam National University , Gwangju , Republic of Korea.
  • Jones DR; b Department of Biochemistry and Molecular Biology , University of Arkansas for Medical Sciences , Little Rock , AR , USA.
  • Kang JY; a School of Biological Sciences and Technology , Chonnam National University , Gwangju , Republic of Korea.
  • Yun CH; a School of Biological Sciences and Technology , Chonnam National University , Gwangju , Republic of Korea.
  • Miller GP; a School of Biological Sciences and Technology , Chonnam National University , Gwangju , Republic of Korea.
Xenobiotica ; 49(4): 397-403, 2019 Apr.
Article in En | MEDLINE | ID: mdl-29543105

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Warfarin / Microsomes, Liver / Glucuronides Limits: Humans Language: En Journal: Xenobiotica Year: 2019 Document type: Article Country of publication: Reino Unido

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Warfarin / Microsomes, Liver / Glucuronides Limits: Humans Language: En Journal: Xenobiotica Year: 2019 Document type: Article Country of publication: Reino Unido