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Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl-1 Proteins.
D de Araujo, Aline; Lim, Junxian; Wu, Kai-Chen; Xiang, Yibin; Good, Andrew C; Skerlj, Renato; Fairlie, David P.
Affiliation
  • D de Araujo A; Division of Chemistry and Structural Biology, ARC Centre of Excellence in Advanced Molecular Imaging , Institute for Molecular Bioscience, The University of Queensland , Brisbane , Queensland 4072 , Australia.
  • Lim J; Division of Chemistry and Structural Biology, ARC Centre of Excellence in Advanced Molecular Imaging , Institute for Molecular Bioscience, The University of Queensland , Brisbane , Queensland 4072 , Australia.
  • Wu KC; Division of Chemistry and Structural Biology, ARC Centre of Excellence in Advanced Molecular Imaging , Institute for Molecular Bioscience, The University of Queensland , Brisbane , Queensland 4072 , Australia.
  • Xiang Y; Noliva Therapeutics LLC , Newton , Massachusetts 02465 , United States.
  • Good AC; Noliva Therapeutics LLC , Newton , Massachusetts 02465 , United States.
  • Skerlj R; Noliva Therapeutics LLC , Newton , Massachusetts 02465 , United States.
  • Fairlie DP; Division of Chemistry and Structural Biology, ARC Centre of Excellence in Advanced Molecular Imaging , Institute for Molecular Bioscience, The University of Queensland , Brisbane , Queensland 4072 , Australia.
J Med Chem ; 61(7): 2962-2972, 2018 04 12.
Article in En | MEDLINE | ID: mdl-29584430
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bridged Bicyclo Compounds / Proto-Oncogene Proteins c-bcl-2 / Myeloid Cell Leukemia Sequence 1 Protein / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2018 Document type: Article Affiliation country: Australia
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bridged Bicyclo Compounds / Proto-Oncogene Proteins c-bcl-2 / Myeloid Cell Leukemia Sequence 1 Protein / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2018 Document type: Article Affiliation country: Australia