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Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies.
Toledo, Rodrigo A; Garralda, Elena; Mitsi, Maria; Pons, Tirso; Monsech, Jorge; Vega, Estela; Otero, Álvaro; Albarran, Maria I; Baños, Natalia; Durán, Yolanda; Bonilla, Victoria; Sarno, Francesca; Camacho-Artacho, Marta; Sanchez-Perez, Tania; Perea, Sofia; Álvarez, Rafael; De Martino, Alba; Lietha, Daniel; Blanco-Aparicio, Carmen; Cubillo, Antonio; Domínguez, Orlando; Martínez-Torrecuadrada, Jorge L; Hidalgo, Manuel.
Affiliation
  • Toledo RA; Gastrointestinal Cancer Clinical Research Unit, Spanish National Cancer Research Center (CNIO), Madrid, Spain. rtoledo@vhio.net.
  • Garralda E; Vall d'Hebron Institute of Oncology (VHIO), CIBERONC, Barcelona, Spain.
  • Mitsi M; Vall d'Hebron Institute of Oncology (VHIO), CIBERONC, Barcelona, Spain.
  • Pons T; Centro Integral Oncológico Clara Campal (CIOCC), Hospital Universitario HM Sanchinarro, Madrid, Spain.
  • Monsech J; Universidad San Pablo CEU, Madrid, Spain.
  • Vega E; Laboratory of Biomolecular Research, Paul Scherrer Institute, Villigen, Switzerland.
  • Otero Á; Structural Computational Biology Group, CNIO, Madrid, Spain.
  • Albarran MI; Genomics Core Unit, CNIO, Madrid, Spain.
  • Baños N; Centro Integral Oncológico Clara Campal (CIOCC), Hospital Universitario HM Sanchinarro, Madrid, Spain.
  • Durán Y; Universidad San Pablo CEU, Madrid, Spain.
  • Bonilla V; Crystallography and Protein Engineering Unit, CNIO, Madrid, Spain.
  • Sarno F; Experimental Therapeutics Programme, CNIO, Madrid, Spain.
  • Camacho-Artacho M; Gastrointestinal Cancer Clinical Research Unit, Spanish National Cancer Research Center (CNIO), Madrid, Spain.
  • Sanchez-Perez T; Gastrointestinal Cancer Clinical Research Unit, Spanish National Cancer Research Center (CNIO), Madrid, Spain.
  • Perea S; Gastrointestinal Cancer Clinical Research Unit, Spanish National Cancer Research Center (CNIO), Madrid, Spain.
  • Álvarez R; Gastrointestinal Cancer Clinical Research Unit, Spanish National Cancer Research Center (CNIO), Madrid, Spain.
  • De Martino A; Cell Signalling and Adhesion Group, CNIO, Madrid, Spain.
  • Lietha D; Molecular Genetics of Angiogenesis Laboratory, Spanish National Center for Cardiovascular Research (CNIC), Madrid, Spain.
  • Blanco-Aparicio C; Gastrointestinal Cancer Clinical Research Unit, Spanish National Cancer Research Center (CNIO), Madrid, Spain.
  • Cubillo A; Centro Integral Oncológico Clara Campal (CIOCC), Hospital Universitario HM Sanchinarro, Madrid, Spain.
  • Domínguez O; Universidad San Pablo CEU, Madrid, Spain.
  • Martínez-Torrecuadrada JL; Histopathology Unit, CNIO, Madrid, Spain.
  • Hidalgo M; Cell Signalling and Adhesion Group, CNIO, Madrid, Spain.
Clin Cancer Res ; 24(15): 3550-3559, 2018 08 01.
Article in En | MEDLINE | ID: mdl-29588308
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Angiogenesis Inhibitors / Vascular Endothelial Growth Factor Receptor-2 / Neovascularization, Pathologic Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2018 Document type: Article Affiliation country: España
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Angiogenesis Inhibitors / Vascular Endothelial Growth Factor Receptor-2 / Neovascularization, Pathologic Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2018 Document type: Article Affiliation country: España