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Induction of a central memory and stem cell memory phenotype in functionally active CD4+ and CD8+ CAR T cells produced in an automated good manufacturing practice system for the treatment of CD19+ acute lymphoblastic leukemia.
Blaeschke, Franziska; Stenger, Dana; Kaeuferle, Theresa; Willier, Semjon; Lotfi, Ramin; Kaiser, Andrew Didier; Assenmacher, Mario; Döring, Michaela; Feucht, Judith; Feuchtinger, Tobias.
Affiliation
  • Blaeschke F; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Dr. von Hauner University Children's Hospital, Ludwig Maximilian University Munich, Lindwurmstrasse 4, 80337, Munich, Germany.
  • Stenger D; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Dr. von Hauner University Children's Hospital, Ludwig Maximilian University Munich, Lindwurmstrasse 4, 80337, Munich, Germany.
  • Kaeuferle T; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Dr. von Hauner University Children's Hospital, Ludwig Maximilian University Munich, Lindwurmstrasse 4, 80337, Munich, Germany.
  • Willier S; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Dr. von Hauner University Children's Hospital, Ludwig Maximilian University Munich, Lindwurmstrasse 4, 80337, Munich, Germany.
  • Lotfi R; Institute for Transfusion Medicine, University Hospital Ulm, Ulm, Germany.
  • Kaiser AD; Institute for Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Services Baden-Württemberg-Hessen, Ulm, Germany.
  • Assenmacher M; Miltenyi Biotec, Bergisch Gladbach, Germany.
  • Döring M; Miltenyi Biotec, Bergisch Gladbach, Germany.
  • Feucht J; Department of Pediatric Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Dr. von Hauner University Children's Hospital, Ludwig Maximilian University Munich, Lindwurmstrasse 4, 80337, Munich, Germany.
  • Feuchtinger T; Department I - General Pediatrics, Hematology/Oncology, University Hospital Tübingen, Children's Hospital, Tübingen, Germany.
Cancer Immunol Immunother ; 67(7): 1053-1066, 2018 07.
Article in En | MEDLINE | ID: mdl-29605883
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Receptors, Antigen, T-Cell / CD4-Positive T-Lymphocytes / CD8-Positive T-Lymphocytes / Antigens, CD19 / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Immunologic Memory Type of study: Guideline / Prognostic_studies Limits: Adolescent / Female / Humans Language: En Journal: Cancer Immunol Immunother Journal subject: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Year: 2018 Document type: Article Affiliation country: Alemania Country of publication: Alemania
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / Receptors, Antigen, T-Cell / CD4-Positive T-Lymphocytes / CD8-Positive T-Lymphocytes / Antigens, CD19 / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Immunologic Memory Type of study: Guideline / Prognostic_studies Limits: Adolescent / Female / Humans Language: En Journal: Cancer Immunol Immunother Journal subject: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Year: 2018 Document type: Article Affiliation country: Alemania Country of publication: Alemania