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Inhibition of IP6K1 suppresses neutrophil-mediated pulmonary damage in bacterial pneumonia.
Hou, Qingming; Liu, Fei; Chakraborty, Anutosh; Jia, Yonghui; Prasad, Amit; Yu, Hongbo; Zhao, Li; Ye, Keqiang; Snyder, Solomon H; Xu, Yuanfu; Luo, Hongbo R.
Affiliation
  • Hou Q; Department of Pathology, Harvard Medical School, Dana-Farber/Harvard Cancer Center; Department of Laboratory Medicine, Children's Hospital Boston, Karp Family Research Building, Room 10214, Boston, MA 02115, USA.
  • Liu F; State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 288 Nanjing Road, Tianjin 300020, China.
  • Chakraborty A; Departments of Neuroscience, Pharmacology and Molecular Sciences, and Psychiatry, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Jia Y; Department of Pathology, Harvard Medical School, Dana-Farber/Harvard Cancer Center; Department of Laboratory Medicine, Children's Hospital Boston, Karp Family Research Building, Room 10214, Boston, MA 02115, USA.
  • Prasad A; Department of Pathology, Harvard Medical School, Dana-Farber/Harvard Cancer Center; Department of Laboratory Medicine, Children's Hospital Boston, Karp Family Research Building, Room 10214, Boston, MA 02115, USA.
  • Yu H; Veterans Affairs Boston Healthcare System, Department of Pathology and Laboratory Medicine, 1400 Veterans of Foreign Wars Parkway, West Roxbury, MA 02132, USA.
  • Zhao L; Department of Pathology, Harvard Medical School, Dana-Farber/Harvard Cancer Center; Department of Laboratory Medicine, Children's Hospital Boston, Karp Family Research Building, Room 10214, Boston, MA 02115, USA.
  • Ye K; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Snyder SH; Departments of Neuroscience, Pharmacology and Molecular Sciences, and Psychiatry, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Xu Y; State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 288 Nanjing Road, Tianjin 300020, China. hongbo.luo@childrens.harvard.edu xuyf@ihcams.ac.cn.
  • Luo HR; Department of Pathology, Harvard Medical School, Dana-Farber/Harvard Cancer Center; Department of Laboratory Medicine, Children's Hospital Boston, Karp Family Research Building, Room 10214, Boston, MA 02115, USA. hongbo.luo@childrens.harvard.edu xuyf@ihcams.ac.cn.
Sci Transl Med ; 10(435)2018 04 04.
Article in En | MEDLINE | ID: mdl-29618559
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphotransferases (Phosphate Group Acceptor) / Pneumonia, Bacterial / Lung / Neutrophils Limits: Animals Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2018 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphotransferases (Phosphate Group Acceptor) / Pneumonia, Bacterial / Lung / Neutrophils Limits: Animals Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2018 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos