Chloroquine inhibits cell growth in human A549 lung cancer cells by blocking autophagy and inducing mitochondrial­mediated apoptosis.

Liu, Likun; Han, Cuicui; Yu, Haitao; Zhu, Wenbin; Cui, Hongxia; Zheng, Lihong; Zhang, Chunjing; Yue, Liling

Chloroquine inhibits cell growth in human A549 lung cancer cells by blocking autophagy and inducing mitochondrialmediated apoptosis.

Liu, Likun; Han, Cuicui; Yu, Haitao; Zhu, Wenbin; Cui, Hongxia; Zheng, Lihong; Zhang, Chunjing; Yue, Liling.

Affiliation

Liu L; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Han C; Department of Pharmacology, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Yu H; Department of Biology Genetics, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Zhu W; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Cui H; Department of Clinical Pharmacology, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Zheng L; Department of Biology Genetics, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Zhang C; Department of Biochemistry, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.
Yue L; Research Institute of Medicine and Pharmacy, Qiqihar Medical University, Qiqihar, Heilongjiang 161006, P.R. China.

Oncol Rep ; 39(6): 2807-2816, 2018 Jun.

Article in En | MEDLINE | ID: mdl-29658606

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chloroquine / Phosphatidylinositol 3-Kinases / Proto-Oncogene Proteins c-akt / Lung Neoplasms / Mitochondria Type of study: Prognostic_studies Limits: Humans Language: En Journal: Oncol Rep Journal subject: NEOPLASIAS Year: 2018 Document type: Article Country of publication: Grecia

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