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LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.
Cobo-Vuilleumier, Nadia; Lorenzo, Petra I; Rodríguez, Noelia García; Herrera Gómez, Irene de Gracia; Fuente-Martin, Esther; López-Noriega, Livia; Mellado-Gil, José Manuel; Romero-Zerbo, Silvana-Yanina; Baquié, Mathurin; Lachaud, Christian Claude; Stifter, Katja; Perdomo, German; Bugliani, Marco; De Tata, Vincenzo; Bosco, Domenico; Parnaud, Geraldine; Pozo, David; Hmadcha, Abdelkrim; Florido, Javier P; Toscano, Miguel G; de Haan, Peter; Schoonjans, Kristina; Sánchez Palazón, Luis; Marchetti, Piero; Schirmbeck, Reinhold; Martín-Montalvo, Alejandro; Meda, Paolo; Soria, Bernat; Bermúdez-Silva, Francisco-Javier; St-Onge, Luc; Gauthier, Benoit R.
Affiliation
  • Cobo-Vuilleumier N; Department of Cell Regeneration and Advanced Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucia-University of Pablo de Olavide-University of Seville-CSIC, Seville, 41092, Spain.
  • Lorenzo PI; Department of Cell Regeneration and Advanced Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucia-University of Pablo de Olavide-University of Seville-CSIC, Seville, 41092, Spain.
  • Rodríguez NG; Department of Cell Regeneration and Advanced Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucia-University of Pablo de Olavide-University of Seville-CSIC, Seville, 41092, Spain.
  • Herrera Gómez IG; Department of Cell Regeneration and Advanced Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucia-University of Pablo de Olavide-University of Seville-CSIC, Seville, 41092, Spain.
  • Fuente-Martin E; Department of Cell Regeneration and Advanced Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucia-University of Pablo de Olavide-University of Seville-CSIC, Seville, 41092, Spain.
  • López-Noriega L; Department of Cell Regeneration and Advanced Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucia-University of Pablo de Olavide-University of Seville-CSIC, Seville, 41092, Spain.
  • Mellado-Gil JM; Department of Cell Regeneration and Advanced Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucia-University of Pablo de Olavide-University of Seville-CSIC, Seville, 41092, Spain.
  • Romero-Zerbo SY; Unidad de Gestión Clínica Intercentros de Endocrinología y Nutrición, Instituto de Investigación Biomédica de Málaga (IBIMA) Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, 29010, Spain.
  • Baquié M; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, 28029, Spain.
  • Lachaud CC; Neurix SA, Geneva, 1228, Switzerland.
  • Stifter K; Department of Cell Regeneration and Advanced Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucia-University of Pablo de Olavide-University of Seville-CSIC, Seville, 41092, Spain.
  • Perdomo G; Ulm University Hospital, Ulm, 89081, Germany.
  • Bugliani M; Facultad de Ciencias de la Salud, Universidad de Burgos, Burgos, 09001, Spain.
  • De Tata V; Department Clinical and Experimental Medicine, University of Pisa-AOUP University Hospital, Pisa, 56126, Italy.
  • Bosco D; Department of Translational Research and of New Surgical and Medical Technologies, University of Pisa, Pisa, 56126, Italy.
  • Parnaud G; Cell Isolation and Transplantation Centre, University Hospital, Geneva, 1211, Switzerland.
  • Pozo D; Cell Isolation and Transplantation Centre, University Hospital, Geneva, 1211, Switzerland.
  • Hmadcha A; Department of Cell Dynamics and Signalling, CABIMER-Andalusian Center for Molecular Biology and Regenerative Medicine, Seville, 41092, Spain.
  • Florido JP; Department of Cell Regeneration and Advanced Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucia-University of Pablo de Olavide-University of Seville-CSIC, Seville, 41092, Spain.
  • Toscano MG; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, 28029, Spain.
  • de Haan P; Clinical Bioinformatics Area, Fundación Progreso y Salud, Consejería de Salud, Seville, 41013, Spain.
  • Schoonjans K; Amarna Therapeutics, Seville, 41092, Spain.
  • Sánchez Palazón L; Amarna Therapeutics, Seville, 41092, Spain.
  • Marchetti P; Laboratory of Metabolic Signaling, EPFL, Lausanne, 1015, Switzerland.
  • Schirmbeck R; Biological Resources, CABIMER-Andalusian Center for Molecular Biology and Regenerative Medicine, Seville, 41092, Spain.
  • Martín-Montalvo A; Department Clinical and Experimental Medicine, University of Pisa-AOUP University Hospital, Pisa, 56126, Italy.
  • Meda P; Ulm University Hospital, Ulm, 89081, Germany.
  • Soria B; Department of Cell Regeneration and Advanced Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucia-University of Pablo de Olavide-University of Seville-CSIC, Seville, 41092, Spain.
  • Bermúdez-Silva FJ; Department of Cell Physiology and Metabolism, University of Geneva, Geneva, 1211, Switzerland.
  • St-Onge L; Department of Cell Regeneration and Advanced Therapies, Andalusian Center for Molecular Biology and Regenerative Medicine-CABIMER, Junta de Andalucia-University of Pablo de Olavide-University of Seville-CSIC, Seville, 41092, Spain.
  • Gauthier BR; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, 28029, Spain.
Nat Commun ; 9(1): 1488, 2018 04 16.
Article in En | MEDLINE | ID: mdl-29662071
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Communication / Receptors, Cytoplasmic and Nuclear / Phenalenes / Diabetes Mellitus, Experimental / Insulin-Secreting Cells / Hypoglycemic Agents Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2018 Document type: Article Affiliation country: España Country of publication: Reino Unido
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Communication / Receptors, Cytoplasmic and Nuclear / Phenalenes / Diabetes Mellitus, Experimental / Insulin-Secreting Cells / Hypoglycemic Agents Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2018 Document type: Article Affiliation country: España Country of publication: Reino Unido