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Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers.
Popovici-Muller, Janeta; Lemieux, René M; Artin, Erin; Saunders, Jeffrey O; Salituro, Francesco G; Travins, Jeremy; Cianchetta, Giovanni; Cai, Zhenwei; Zhou, Ding; Cui, Dawei; Chen, Ping; Straley, Kimberly; Tobin, Erica; Wang, Fang; David, Muriel D; Penard-Lacronique, Virginie; Quivoron, Cyril; Saada, Véronique; de Botton, Stéphane; Gross, Stefan; Dang, Lenny; Yang, Hua; Utley, Luke; Chen, Yue; Kim, Hyeryun; Jin, Shengfang; Gu, Zhiwei; Yao, Gui; Luo, Zhiyong; Lv, Xiaobing; Fang, Cheng; Yan, Liping; Olaharski, Andrew; Silverman, Lee; Biller, Scott; Su, Shin-San M; Yen, Katharine.
Affiliation
  • Popovici-Muller J; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Lemieux RM; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Artin E; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Saunders JO; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Salituro FG; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Travins J; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Cianchetta G; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Cai Z; PharmaResources, Shanghai 201201, China.
  • Zhou D; PharmaResources, Shanghai 201201, China.
  • Cui D; PharmaResources, Shanghai 201201, China.
  • Chen P; PharmaResources, Shanghai 201201, China.
  • Straley K; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Tobin E; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Wang F; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • David MD; INSERM U1170 and Gustave Roussy, Villejuif 94800, France.
  • Penard-Lacronique V; INSERM U1170 and Gustave Roussy, Villejuif 94800, France.
  • Quivoron C; INSERM U1170 and Gustave Roussy, Villejuif 94800, France.
  • Saada V; INSERM U1170 and Gustave Roussy, Villejuif 94800, France.
  • de Botton S; INSERM U1170 and Gustave Roussy, Villejuif 94800, France.
  • Gross S; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Dang L; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Yang H; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Utley L; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Chen Y; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Kim H; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Jin S; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Gu Z; ChemPartner, Shanghai 201203, China.
  • Yao G; ChemPartner, Shanghai 201203, China.
  • Luo Z; ChemPartner, Shanghai 201203, China.
  • Lv X; ChemPartner, Shanghai 201203, China.
  • Fang C; ChemPartner, Shanghai 201203, China.
  • Yan L; ChemPartner, Shanghai 201203, China.
  • Olaharski A; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Silverman L; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Biller S; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Su SM; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
  • Yen K; Agios Pharmaceuticals Inc., Cambridge, Massachusetts 02139, United States.
ACS Med Chem Lett ; 9(4): 300-305, 2018 Apr 12.
Article in En | MEDLINE | ID: mdl-29670690
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2018 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2018 Document type: Article Affiliation country: Estados Unidos Country of publication: Estados Unidos