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A GWAS meta-analysis from 5 population-based cohorts implicates ion channel genes in the pathogenesis of irritable bowel syndrome.
Bonfiglio, F; Henström, M; Nag, A; Hadizadeh, F; Zheng, T; Cenit, M C; Tigchelaar, E; Williams, F; Reznichenko, A; Ek, W E; Rivera, N V; Homuth, G; Aghdassi, A A; Kacprowski, T; Männikkö, M; Karhunen, V; Bujanda, L; Rafter, J; Wijmenga, C; Ronkainen, J; Hysi, P; Zhernakova, A; D'Amato, M.
Affiliation
  • Bonfiglio F; Department of Gastrointestinal and Liver Diseases, Biodonostia Health Research Institute, Spain.
  • Henström M; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
  • Nag A; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
  • Hadizadeh F; Department of Twin Research & Genetic Epidemiology, King's College London, London, England.
  • Zheng T; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
  • Cenit MC; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
  • Tigchelaar E; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.
  • Williams F; Department of Genetics, University Medical Center Groningen, Groningen, The Netherlands.
  • Reznichenko A; Department of Twin Research & Genetic Epidemiology, King's College London, London, England.
  • Ek WE; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
  • Rivera NV; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
  • Homuth G; Department of Immunology, Genetics and Pathology, Science for Life Laboratory Uppsala, Uppsala University, Uppsala, Sweden.
  • Aghdassi AA; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
  • Kacprowski T; Department of Functional Genomics, Interfaculty Institute of Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
  • Männikkö M; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany.
  • Karhunen V; Department of Functional Genomics, Interfaculty Institute of Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
  • Bujanda L; Center for Life Course Health Research, University of Oulu, Oulu, Finland.
  • Rafter J; Center for Life Course Health Research, University of Oulu, Oulu, Finland.
  • Wijmenga C; Oulu University Hospital, Oulu, Finland.
  • Ronkainen J; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.
  • Hysi P; Department of Gastrointestinal and Liver Diseases, Biodonostia Health Research Institute, Spain.
  • Zhernakova A; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Universidad del País Vasco (UPV/EHU), San Sebastián, Spain.
  • D'Amato M; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
Neurogastroenterol Motil ; 30(9): e13358, 2018 09.
Article in En | MEDLINE | ID: mdl-29673008
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Predisposition to Disease / Irritable Bowel Syndrome / Genome-Wide Association Study / Ion Channels Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Neurogastroenterol Motil Journal subject: GASTROENTEROLOGIA / NEUROLOGIA Year: 2018 Document type: Article Affiliation country: España Country of publication: Reino Unido
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Genetic Predisposition to Disease / Irritable Bowel Syndrome / Genome-Wide Association Study / Ion Channels Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Neurogastroenterol Motil Journal subject: GASTROENTEROLOGIA / NEUROLOGIA Year: 2018 Document type: Article Affiliation country: España Country of publication: Reino Unido