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HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types.
Zirkel, Anne; Nikolic, Milos; Sofiadis, Konstantinos; Mallm, Jan-Philipp; Brackley, Chris A; Gothe, Henrike; Drechsel, Oliver; Becker, Christian; Altmüller, Janine; Josipovic, Natasa; Georgomanolis, Theodore; Brant, Lilija; Franzen, Julia; Koker, Mirjam; Gusmao, Eduardo G; Costa, Ivan G; Ullrich, Roland T; Wagner, Wolfgang; Roukos, Vassilis; Nürnberg, Peter; Marenduzzo, Davide; Rippe, Karsten; Papantonis, Argyris.
Affiliation
  • Zirkel A; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany.
  • Nikolic M; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany.
  • Sofiadis K; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany.
  • Mallm JP; German Cancer Research Center and Bioquant, 69120 Heidelberg, Germany.
  • Brackley CA; School of Physics and Astronomy, University of Edinburgh, EH9 3FD Edinburgh, UK.
  • Gothe H; Institute of Molecular Biology, 55128 Mainz, Germany.
  • Drechsel O; Institute of Molecular Biology, 55128 Mainz, Germany.
  • Becker C; Cologne Center for Genomics, University of Cologne, 50931 Cologne, Germany.
  • Altmüller J; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany; Cologne Center for Genomics, University of Cologne, 50931 Cologne, Germany.
  • Josipovic N; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany.
  • Georgomanolis T; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany.
  • Brant L; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany.
  • Franzen J; Helmholtz Institute for Biomedical Engineering, RWTH Aachen University Medical School, 52074 Aachen, Germany.
  • Koker M; Clinic I of Internal Medicine and Center for Integrated Oncology, University Hospital Cologne, 50931 Cologne, Germany.
  • Gusmao EG; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany; Interdisciplinary Centre for Clinical Research, RWTH Aachen University Medical School, 52062 Aachen, Germany.
  • Costa IG; Interdisciplinary Centre for Clinical Research, RWTH Aachen University Medical School, 52062 Aachen, Germany.
  • Ullrich RT; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany; Clinic I of Internal Medicine and Center for Integrated Oncology, University Hospital Cologne, 50931 Cologne, Germany.
  • Wagner W; Helmholtz Institute for Biomedical Engineering, RWTH Aachen University Medical School, 52074 Aachen, Germany.
  • Roukos V; Institute of Molecular Biology, 55128 Mainz, Germany.
  • Nürnberg P; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany; Cologne Center for Genomics, University of Cologne, 50931 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, German
  • Marenduzzo D; School of Physics and Astronomy, University of Edinburgh, EH9 3FD Edinburgh, UK.
  • Rippe K; German Cancer Research Center and Bioquant, 69120 Heidelberg, Germany.
  • Papantonis A; Center for Molecular Medicine Cologne, University of Cologne, 50931 Cologne, Germany. Electronic address: argyris.papantonis@uni-koeln.de.
Mol Cell ; 70(4): 730-744.e6, 2018 05 17.
Article in En | MEDLINE | ID: mdl-29706538

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Genome, Human / HMGB2 Protein / CCCTC-Binding Factor Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2018 Document type: Article Affiliation country: Alemania Country of publication: Estados Unidos

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Genome, Human / HMGB2 Protein / CCCTC-Binding Factor Type of study: Prognostic_studies Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2018 Document type: Article Affiliation country: Alemania Country of publication: Estados Unidos