Maternal obesity alters the expression of embryonic regulatory transcripts in the preimplantation ovine conceptus.
Reprod Biol
; 18(2): 198-201, 2018 Jun.
Article
in En
| MEDLINE
| ID: mdl-29764739
ABSTRACT
The influence of exposure to overfeeding-induced maternal obesity around the time of conception on early embryogenesis was examined in the day 14 ovine conceptus. The relative abundance of FGFR2 and DNMT1 was influenced by maternal obesity status and conceptus sex, and the abundance of PPARG and PTGS2 transcripts was greater in male conceptuses regardless of the obesity status of the ewe. These observations demonstrated that short-term exposure to maternal obesity impacts early conceptus transcript patterning.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Blastocyst
/
Maternal Nutritional Physiological Phenomena
/
PPAR gamma
/
Cyclooxygenase 2
/
Receptor, Fibroblast Growth Factor, Type 2
/
DNA (Cytosine-5-)-Methyltransferase 1
Limits:
Animals
/
Pregnancy
Language:
En
Journal:
Reprod Biol
Journal subject:
MEDICINA REPRODUTIVA
Year:
2018
Document type:
Article
Affiliation country:
Estados Unidos