Current Methods for Skeletal Muscle Tissue Repair and Regeneration.
Biomed Res Int
; 2018: 1984879, 2018.
Article
in En
| MEDLINE
| ID: mdl-29850487
ABSTRACT
Skeletal muscle has the capacity of regeneration after injury. However, for large volumes of muscle loss, this regeneration needs interventional support. Consequently, muscle injury provides an ongoing reconstructive and regenerative challenge in clinical work. To promote muscle repair and regeneration, different strategies have been developed within the last century and especially during the last few decades, including surgical techniques, physical therapy, biomaterials, and muscular tissue engineering as well as cell therapy. Still, there is a great need to develop new methods and materials, which promote skeletal muscle repair and functional regeneration. In this review, we give a comprehensive overview over the epidemiology of muscle tissue loss, highlight current strategies in clinical treatment, and discuss novel methods for muscle regeneration and challenges for their future clinical translation.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Regeneration
/
Muscle, Skeletal
/
Tissue Engineering
Limits:
Animals
/
Humans
Language:
En
Journal:
Biomed Res Int
Year:
2018
Document type:
Article
Affiliation country:
Alemania