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Targeting the mitochondrial VDAC in hepatocellular carcinoma using a polyclonal antibody-conjugated to a nitrosyl ruthenium complex.
Ramos, Loyanne C B; Rodrigues, Fernando P; Biazzotto, Juliana C; de Paula Machado, Sergio; Slep, Leonardo D; Hamblin, Michael R; da Silva, Roberto S.
Affiliation
  • Ramos LCB; Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
  • Rodrigues FP; Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
  • Biazzotto JC; Departamento de Física e Química, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
  • de Paula Machado S; Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, 21941-590, Brazil.
  • Slep LD; Departamento de Química Inorgánica, Analítica y Química Física and INQUIMAE, CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, Ciudad Universitaria, C1428EHA, Buenos Aires, Argentina.
  • Hamblin MR; Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Boston, MA, 02114, USA.
  • da Silva RS; Department of Dermatology, Harvard Medical School, Boston, MA, 02115, USA.
J Biol Inorg Chem ; 23(6): 903-916, 2018 08.
Article in En | MEDLINE | ID: mdl-29971501
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ruthenium / Mitochondria, Liver / Carcinoma, Hepatocellular / Immunoconjugates / Voltage-Dependent Anion Channels / Liver Neoplasms / Antibodies Limits: Animals / Humans / Male Language: En Journal: J Biol Inorg Chem Journal subject: BIOQUIMICA Year: 2018 Document type: Article Affiliation country: Brasil
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ruthenium / Mitochondria, Liver / Carcinoma, Hepatocellular / Immunoconjugates / Voltage-Dependent Anion Channels / Liver Neoplasms / Antibodies Limits: Animals / Humans / Male Language: En Journal: J Biol Inorg Chem Journal subject: BIOQUIMICA Year: 2018 Document type: Article Affiliation country: Brasil