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Multitargeted kinase inhibitors imatinib, sorafenib and sunitinib perturb energy metabolism and cause cytotoxicity to cultured C2C12 skeletal muscle derived myotubes.
Damaraju, Vijaya L; Kuzma, Michelle; Cass, Carol E; Putman, Charles T; Sawyer, Michael B.
Affiliation
  • Damaraju VL; Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Ave NW, Edmonton, Alberta T6G1Z2, Canada. Electronic address: vd1@ualberta.ca.
  • Kuzma M; Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Ave NW, Edmonton, Alberta T6G1Z2, Canada. Electronic address: michelle.kuzma@ahs.ca.
  • Cass CE; Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Ave NW, Edmonton, Alberta T6G1Z2, Canada. Electronic address: ccass@ualberta.ca.
  • Putman CT; Faculty of Kinesiology, Sport, and Recreation| Medicine & Dentistry, University of Alberta, Edmonton, Alberta T6G2H9, Canada. Electronic address: tputman@ualberta.ca.
  • Sawyer MB; Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Ave NW, Edmonton, Alberta T6G1Z2, Canada; Department of Medical Oncology, Cross Cancer Institute, 11560 University Avenue NW, Edmonton, Alberta T6G1Z2, Canada. Electronic address: msawyer@ualberta.ca.
Biochem Pharmacol ; 155: 162-171, 2018 09.
Article in En | MEDLINE | ID: mdl-29983397
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Muscle Fibers, Skeletal / Protein Kinase Inhibitors / Energy Metabolism / Imatinib Mesylate / Sorafenib / Sunitinib Limits: Animals Language: En Journal: Biochem Pharmacol Year: 2018 Document type: Article Country of publication: Reino Unido
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Muscle Fibers, Skeletal / Protein Kinase Inhibitors / Energy Metabolism / Imatinib Mesylate / Sorafenib / Sunitinib Limits: Animals Language: En Journal: Biochem Pharmacol Year: 2018 Document type: Article Country of publication: Reino Unido