Hydroxylated and sulfated metabolites of commonly observed airborne polychlorinated biphenyls display selective uptake and toxicity in N27, SH-SY5Y, and HepG2 cells.

Rodriguez, Eric A; Vanle, Brigitte C; Doorn, Jonathan A; Lehmler, Hans-Joachim; Robertson, Larry W; Duffel, Michael W

Rodriguez, Eric A; Vanle, Brigitte C; Doorn, Jonathan A; Lehmler, Hans-Joachim; Robertson, Larry W; Duffel, Michael W.

Affiliation

Rodriguez EA; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, The University of Iowa, Iowa City, IA, 52242, United States.
Vanle BC; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, The University of Iowa, Iowa City, IA, 52242, United States.
Doorn JA; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, The University of Iowa, Iowa City, IA, 52242, United States.
Lehmler HJ; Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, Iowa City, IA, 52242, United States.
Robertson LW; Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, Iowa City, IA, 52242, United States.
Duffel MW; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, The University of Iowa, Iowa City, IA, 52242, United States. Electronic address: michael-duffel@uiowa.edu.

Environ Toxicol Pharmacol ; 62: 69-78, 2018 Sep.

Article in En | MEDLINE | ID: mdl-29986280

Subject(s)
Key words

Hepatotoxicity; Hydroxy PCB; Neurotoxicity; OH-PCB; PCB; PCB sulfate

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfates / Polychlorinated Biphenyls / Air Pollutants Limits: Animals / Humans Language: En Journal: Environ Toxicol Pharmacol Year: 2018 Document type: Article Affiliation country: Estados Unidos

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