Conditional loss of Kcnj13 in the retinal pigment epithelium causes photoreceptor degeneration.

Roman, Dany; Zhong, Hua; Yaklichkin, Sergey; Chen, Rui; Mardon, Graeme

Roman, Dany; Zhong, Hua; Yaklichkin, Sergey; Chen, Rui; Mardon, Graeme.

Affiliation

Roman D; Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, TX, 77030-3411, USA.
Zhong H; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, 77030-3411, USA.
Yaklichkin S; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, 77030-3411, USA.
Chen R; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030-3411, USA; Program in Developmental Biology, Baylor College of Medicine, Houston, TX, 77030-3411, USA; Department of Ophthalmology, Baylor College of Medicine, Houston, TX, 77030-3411, USA.
Mardon G; Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, TX, 77030-3411, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030-3411, USA; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, 7

Exp Eye Res ; 176: 219-226, 2018 11.

Article in En | MEDLINE | ID: mdl-30009826

Subject(s)
Key words

Conditional knockout; KCNJ13; Kir7.1; Leber congenital amaurosis; Photoreceptors; RPE; Retinal degeneration; Retinal function

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Retinal Degeneration / Photoreceptor Cells, Vertebrate / Potassium Channels, Inwardly Rectifying / Retinal Pigment Epithelium Type of study: Etiology_studies Limits: Animals Language: En Journal: Exp Eye Res Year: 2018 Document type: Article Affiliation country: Estados Unidos

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