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Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer.
Patten, Darren K; Corleone, Giacomo; Gyorffy, Balázs; Perone, Ylenia; Slaven, Neil; Barozzi, Iros; Erdos, Edina; Saiakhova, Alina; Goddard, Kate; Vingiani, Andrea; Shousha, Sami; Pongor, Lorinc Sándor; Hadjiminas, Dimitri J; Schiavon, Gaia; Barry, Peter; Palmieri, Carlo; Coombes, Raul C; Scacheri, Peter; Pruneri, Giancarlo; Magnani, Luca.
Affiliation
  • Patten DK; Department of Surgery and Cancer, The Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, UK.
  • Corleone G; Department of Surgery and Cancer, The Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, UK.
  • Gyorffy B; MTA TTK Lendület Cancer Biomarker Research Group, Institute of Enzymology, Hungarian Academy of Sciences, Budapest, Hungary.
  • Perone Y; Semmelweis University, 2nd Deptartment of Pediatrics, Budapest, Hungary.
  • Slaven N; Department of Surgery and Cancer, The Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, UK.
  • Barozzi I; Department of Surgery and Cancer, The Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, UK.
  • Erdos E; Department of Surgery and Cancer, The Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, UK.
  • Saiakhova A; Department of Biochemistry and Molecular Biology, Genomic Medicine and Bioinformatic Core Facility, University of Debrecen, Debrecen, Hungary.
  • Goddard K; Department of Genetics and Genome Sciences, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA.
  • Vingiani A; Department of Breast and General Surgery, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, UK.
  • Shousha S; Department of Pathology, European Institute of Oncology, Milan, Italy.
  • Pongor LS; Centre for Pathology, Department of Medicine, Imperial College London, London, UK.
  • Hadjiminas DJ; MTA TTK Lendület Cancer Biomarker Research Group, Institute of Enzymology, Hungarian Academy of Sciences, Budapest, Hungary.
  • Schiavon G; Centre for Pathology, Department of Medicine, Imperial College London, London, UK.
  • Barry P; IMED Biotech Unit, AstraZeneca, Cambridge, UK.
  • Palmieri C; Department of Breast Surgery, The Royal Marsden NHS Foundation Trust, Sutton, UK.
  • Coombes RC; Institute of Translational Medicine University of Liverpool, Clatterbridge Cancer Centre, NHS Foundation Trust, and Royal Liverpool University Hospital, Liverpool, Merseyside, UK.
  • Scacheri P; Department of Surgery and Cancer, The Imperial Centre for Translational and Experimental Medicine, Imperial College London, London, UK.
  • Pruneri G; Department of Genetics and Genome Sciences, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA.
  • Magnani L; Pathology Department, Fondazione IRCCS Istituto Nazionale Tumori and University of Milan, School of Medicine, Milan, Italy.
Nat Med ; 24(9): 1469-1480, 2018 09.
Article in En | MEDLINE | ID: mdl-30038216
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Enhancer Elements, Genetic / Clonal Evolution Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2018 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Enhancer Elements, Genetic / Clonal Evolution Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2018 Document type: Article Affiliation country: Reino Unido Country of publication: Estados Unidos