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Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma.
MacGregor, Stuart; Ong, Jue-Sheng; An, Jiyuan; Han, Xikun; Zhou, Tiger; Siggs, Owen M; Law, Matthew H; Souzeau, Emmanuelle; Sharma, Shiwani; Lynn, David J; Beesley, Jonathan; Sheldrick, Bronwyn; Mills, Richard A; Landers, John; Ruddle, Jonathan B; Graham, Stuart L; Healey, Paul R; White, Andrew J R; Casson, Robert J; Best, Stephen; Grigg, John R; Goldberg, Ivan; Powell, Joseph E; Whiteman, David C; Radford-Smith, Graham L; Martin, Nicholas G; Montgomery, Grant W; Burdon, Kathryn P; Mackey, David A; Gharahkhani, Puya; Craig, Jamie E; Hewitt, Alex W.
Affiliation
  • MacGregor S; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. stuart.macgregor@qimrberghofer.edu.au.
  • Ong JS; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • An J; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Han X; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Zhou T; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, South Australia, Australia.
  • Siggs OM; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, South Australia, Australia.
  • Law MH; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Souzeau E; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, South Australia, Australia.
  • Sharma S; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, South Australia, Australia.
  • Lynn DJ; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
  • Beesley J; EMBL Australia Group, Infection & Immunity Theme, South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.
  • Sheldrick B; College of Medicine and Public Health, Flinders University, Bedford Park, South Australia, Australia.
  • Mills RA; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Landers J; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, South Australia, Australia.
  • Ruddle JB; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, South Australia, Australia.
  • Graham SL; Department of Ophthalmology, Flinders University, Flinders Medical Centre, Bedford Park, South Australia, Australia.
  • Healey PR; Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia.
  • White AJR; Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales, Australia.
  • Casson RJ; Centre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.
  • Best S; Discipline of Ophthalmology, Faculty of Medicine & Health Sciences, University of Sydney, Sydney Eye Hospital, Sydney, New South Wales, Australia.
  • Grigg JR; Centre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.
  • Goldberg I; South Australian Institute of Ophthalmology, University of Adelaide, Adelaide, South Australia, Australia.
  • Powell JE; Eye Department, Greenlane Clinical Centre, Auckland District Health Board, Auckland, New Zealand.
  • Whiteman DC; Discipline of Ophthalmology, Faculty of Medicine & Health Sciences, University of Sydney, Sydney Eye Hospital, Sydney, New South Wales, Australia.
  • Radford-Smith GL; Discipline of Ophthalmology, Faculty of Medicine & Health Sciences, University of Sydney, Sydney Eye Hospital, Sydney, New South Wales, Australia.
  • Martin NG; Garvan-Weizmann Centre for Cellular Genomics, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
  • Montgomery GW; St Vincent's Clinical School, University of New South Wales, Sydney, New South Wales, Australia.
  • Burdon KP; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Mackey DA; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Gharahkhani P; University of Queensland School of Medicine, Brisbane, Queensland, Australia.
  • Craig JE; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
  • Hewitt AW; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
Nat Genet ; 50(8): 1067-1071, 2018 08.
Article in En | MEDLINE | ID: mdl-30054594
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glaucoma / Intraocular Pressure Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2018 Document type: Article Affiliation country: Australia Country of publication: Estados Unidos
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glaucoma / Intraocular Pressure Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male Language: En Journal: Nat Genet Journal subject: GENETICA MEDICA Year: 2018 Document type: Article Affiliation country: Australia Country of publication: Estados Unidos