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Soluble B7-H3 (sB7-H3) is over-expressed in the serum of type 1 diabetes patients.
Fang, Chen; Li, Sicheng; Xu, Rongqin; Guo, Heming; Jiang, Rong; Ding, Sisi; Chen, Xiaohong; Huang, Yun; Hu, Ji; Liu, Cuiping; Tu, Yifeng.
Affiliation
  • Fang C; College of Chemistry, Chemical Engineering and Materials, Soochow University, Suzhou 215123, PR China; Department of Endocrinology, Second Affiliated Hospital of Soochow University, Suzhou 215004, PR China. Electronic address: afa9911@sina.com.
  • Li S; Department of Endocrinology, Second Affiliated Hospital of Soochow University, Suzhou 215004, PR China.
  • Xu R; Department of Clinical Laboratory, The Seventh People's Hospital of Suzhou, 215151, PR China.
  • Guo H; Department of Endocrinology, Second Affiliated Hospital of Soochow University, Suzhou 215004, PR China.
  • Jiang R; Department of Endocrinology, Second Affiliated Hospital of Soochow University, Suzhou 215004, PR China.
  • Ding S; Jiangsu Institute of Clinical Immunology & Jiangsu Key Laboratory of Clinical Immunology, First Affiliated Hospital of Soochow University, Suzhou 215006, PR China.
  • Chen X; Department of Endocrinology, Second Affiliated Hospital of Soochow University, Suzhou 215004, PR China.
  • Huang Y; Department of Endocrinology, Second Affiliated Hospital of Soochow University, Suzhou 215004, PR China.
  • Hu J; Department of Endocrinology, Second Affiliated Hospital of Soochow University, Suzhou 215004, PR China.
  • Liu C; Jiangsu Institute of Clinical Immunology & Jiangsu Key Laboratory of Clinical Immunology, First Affiliated Hospital of Soochow University, Suzhou 215006, PR China. Electronic address: liucuiping1980@126.com.
  • Tu Y; College of Chemistry, Chemical Engineering and Materials, Soochow University, Suzhou 215123, PR China.
Diabetes Res Clin Pract ; 143: 332-336, 2018 Sep.
Article in En | MEDLINE | ID: mdl-30081105
ABSTRACT
Type 1 Diabetes (T1D) is an autoimmune disease resulting from insulin-secreting ß-cells mediated by autoreactive T cells. We demonstrated increased level of sB7-H3 in T1D patients than in healthy control group. This result suggests that B7-H3 may be may be a promising biomarker associated with the pathogenesis of T1D.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / Diabetes Mellitus, Type 1 / B7 Antigens Limits: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Language: En Journal: Diabetes Res Clin Pract Journal subject: ENDOCRINOLOGIA Year: 2018 Document type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biomarkers / Diabetes Mellitus, Type 1 / B7 Antigens Limits: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Language: En Journal: Diabetes Res Clin Pract Journal subject: ENDOCRINOLOGIA Year: 2018 Document type: Article